PMID- 15311350 OWN - NLM STAT- MEDLINE DCOM- 20040928 LR - 20131121 IS - 0340-5354 (Print) IS - 0340-5354 (Linking) VI - 251 IP - 6 DP - 2004 Jun TI - The primary motor area for voluntary diaphragmatic motion identified by high field fMRI. PG - 730-5 AB - In order to identify the precise location of the primary motor area for the diaphragm with respect to the classical motor homunculus, functional magnetic resonance imaging (fMRI) experiments were performed utilizing independent component-cross correlation- sequential epoch (ICS) analysis on a high-field (3.0 Tesla) system. Activations which correlated with voluntary diaphragmatic motion mapped onto the area anterolateral to that for voluntary hand motion (internal control in ICS analysis). Multiple subject analysis yielded the primary motor cortex for the diaphragm to be (+/-48, -4, 47) in the Talairach and Tournoux coordinates. The results were highly consistent with the previously reported cortical area for the diaphragm determined by transcranial electrical/magnetic stimulation. FAU - Nakayama, Takahiro AU - Nakayama T AD - Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, 1-757 Asahimachi, Niigata 951-8585, Japan. FAU - Fujii, Yukihiko AU - Fujii Y FAU - Suzuki, Kiyotaka AU - Suzuki K FAU - Kanazawa, Ichiro AU - Kanazawa I FAU - Nakada, Tsutomu AU - Nakada T LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - J Neurol JT - Journal of neurology JID - 0423161 RN - S88TT14065 (Oxygen) SB - IM MH - Adult MH - Brain Mapping MH - Diaphragm/*physiology MH - Echo-Planar Imaging/methods MH - Female MH - Hand/physiology MH - Humans MH - Magnetic Resonance Imaging/*methods MH - Male MH - *Motion MH - Motor Cortex/blood supply/*physiology MH - Oxygen/blood EDAT- 2004/08/18 05:00 MHDA- 2004/09/29 05:00 CRDT- 2004/08/18 05:00 PHST- 2003/03/19 00:00 [received] PHST- 2004/01/14 00:00 [revised] PHST- 2004/01/21 00:00 [accepted] PHST- 2004/08/18 05:00 [pubmed] PHST- 2004/09/29 05:00 [medline] PHST- 2004/08/18 05:00 [entrez] AID - 10.1007/s00415-004-0413-4 [doi] PST - ppublish SO - J Neurol. 2004 Jun;251(6):730-5. doi: 10.1007/s00415-004-0413-4.