PMID- 15325158
OWN - NLM
STAT- MEDLINE
DCOM- 20041005
LR  - 20131121
IS  - 0048-9697 (Print)
IS  - 0048-9697 (Linking)
VI  - 330
IP  - 1-3
DP  - 2004 Sep 1
TI  - Circumpolar maternal blood contaminant survey, 1994-1997 organochlorine 
      compounds.
PG  - 55-70
AB  - During the past 20 years a number of studies have found neurological and 
      immunological effects in the developing fetus and infants exposed to background 
      or only slightly elevated levels of persistent organic pollutants (POPs) such as 
      polychlorinated biphenyls (PCBs). To address concerns arising from possible 
      increased human exposure in the Arctic and possible effects of POPs, all 
      circumpolar countries agreed in 1994 to monitoring of specific human tissues for 
      contaminants in the Arctic under the Arctic Monitoring and Assessment Program 
      (AMAP). Mothers in eight circumpolar countries contributed blood samples that 
      were analysed at a single laboratory for 14 PCB congeners (IUPAC No. 28, 52, 99, 
      105, 118, 128, 138, 153, 156, 170, 180, 183, 187) and 13 organochlorine 
      pesticides (aldrin, beta-hexachlorocyclohexane (beta-HCH), 
      dichlordiphenyltrichloroethane (p,p'-DDT), diphenyldichloroethylene (p,p'-DDE), 
      dieldrin, heptachlorepoxide, hexachlorobenzene (HCB), mirex, and the chlordane 
      derivatives alpha-chlordane, gamma-chlordane, cis-nonachlor, oxychlordane and 
      trans-nonachlor). Inuit mothers from Greenland and Canada have significantly 
      higher levels of oxychlordane, transnonachlor and mirex than mothers from Norway, 
      Sweden, Iceland and Russia. Inuit mothers from Greenland also have significantly 
      higher levels of these contaminants than Inuit mothers from Canada and Alaska. 
      These differences among Inuit groups may represent regional dietary preferences 
      or different contaminant deposition patterns across the Arctic. Levels of PCBs 
      are also elevated among some arctic populations due to their consumption of 
      marine mammals and are in the range where subtle effects on learning and the 
      immune system have been reported. The Russian mothers who consume mainly food 
      imported from southern Russia have elevated levels of DDT, DDE, beta-HCH and a 
      higher proportion of lower chlorinated PCB congeners. This study has allowed an 
      assessment of the variation of contaminants such as PCBs and various 
      organochlorine pesticides (DDT, chlordane, etc.) in human populations around the 
      circumpolar north.
FAU - Van Oostdam, J C
AU  - Van Oostdam JC
AD  - Safe Environment Program, Health Canada, PL 0801A2, Ottawa, ON K1A OL2. 
      jay_van_oostdam@hc-sc.gc.ca
FAU - Dewailly, E
AU  - Dewailly E
FAU - Gilman, A
AU  - Gilman A
FAU - Hansen, J C
AU  - Hansen JC
FAU - Odland, J O
AU  - Odland JO
FAU - Chashchin, V
AU  - Chashchin V
FAU - Berner, J
AU  - Berner J
FAU - Butler-Walker, J
AU  - Butler-Walker J
FAU - Lagerkvist, B J
AU  - Lagerkvist BJ
FAU - Olafsdottir, K
AU  - Olafsdottir K
FAU - Soininen, L
AU  - Soininen L
FAU - Bjerregard, P
AU  - Bjerregard P
FAU - Klopov, V
AU  - Klopov V
FAU - Weber, J P
AU  - Weber JP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
RN  - 0 (Insecticides)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adult
MH  - Arctic Regions
MH  - Data Collection
MH  - *Diet
MH  - *Environmental Exposure
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Humans
MH  - Insecticides/*blood
MH  - Polychlorinated Biphenyls/*blood
MH  - Pregnancy
EDAT- 2004/08/25 05:00
MHDA- 2004/10/06 09:00
CRDT- 2004/08/25 05:00
PHST- 2003/03/28 00:00 [received]
PHST- 2003/12/05 00:00 [revised]
PHST- 2004/02/05 00:00 [accepted]
PHST- 2004/08/25 05:00 [pubmed]
PHST- 2004/10/06 09:00 [medline]
PHST- 2004/08/25 05:00 [entrez]
AID - S0048-9697(04)00268-2 [pii]
AID - 10.1016/j.scitotenv.2004.02.028 [doi]
PST - ppublish
SO  - Sci Total Environ. 2004 Sep 1;330(1-3):55-70. doi: 
      10.1016/j.scitotenv.2004.02.028.