PMID- 15329204
OWN - NLM
STAT- MEDLINE
DCOM- 20050426
LR  - 20191210
IS  - 1007-3418 (Print)
IS  - 1007-3418 (Linking)
VI  - 12
IP  - 8
DP  - 2004 Aug
TI  - [Expression analysis of mouse homologous proteins with human aldose reductase 
      like-1].
PG  - 463-6
AB  - OBJECTIVE: To detect expression of mouse ARL-1 homologous proteins in mouse 
      tissues, and analyze homology, genetic distance and phylogenetic relationship 
      between human aldose reductase like-1 (ARL-1) and mouse homologous proteins. 
      METHODS: Homology of mouse ARL-1 homologous proteins with human ARL-1 was 
      analyzed by software Clustal X 1.8 using GenBank and Swiss-Prot database; genetic 
      distance and phylogenetic relationship between mouse ARL-1 homologous proteins 
      and human ARL-1 were analyzed by software Mega 2.0; mouse tissues were detected 
      by Western blotting using polyclonal antibodies against ARL-1 protein from 
      domestic rabbits. RESULTS: The amino acid sequence of human ARL-1 was 83%, 82%, 
      81%, 79%, 70%, 51%, 50% and 45% identical to that of the Chinese hamster ovary 
      reductase (CHO-Red), the mouse fibroblast growth factor-regulated protein (FR-1), 
      rat aldose reductase-like protein (rARLP), the mouse vas deferens protein (MVDP), 
      rat lens aldose reductase (LeAR), delta4-3-ketosteroid-5beta-reductase 
      (5beta-Red), rat aldo-keto reductase protein c (RaK-c) and 3alpha-hydroxysteroid 
      dehydrogenase (3alpha-HSD). Among all the mouse ARL-1 homologous proteins, the 
      genetic distance between CHO-Red and human ARL was the shortest (18.0%, P = 
      0.023), next was FR-1 (19.1%, P=0.023) and rARLP (19.9%, P = 0.025). From the 
      phylogenetic tree, the protein whose relationship with human ARL-1 was the 
      closest with CHO-Red, next was mouse FR-1, rARLP, MVDP and LeAR. Homologous 
      proteins were found in mouse tissues including vas deferens, testis, bladder and 
      uterus by Western blotting using polyclonal antibodies against ARL-1 protein from 
      domestic rabbits. CONCLUSIONS: CHO-Red has the highest homology, the shortest 
      genetic distance and the closest relationship with human ARL-1, next is FR-1, 
      rARLP, MVDP. The major distribution of mouse ARL-1 homologous proteins is in vas 
      deferens, testis, bladder and uterus, deducing they might be CHO-Red, FR-1, rARLP 
      or MVDP
FAU - Jin, Jun-fei
AU  - Jin JF
AD  - Provincial Medical Key Lab of Gene Diagnosis and Therapy; Genetics Research 
      Center, Southeast University Medical School, Nanjing 210009, China.
FAU - Yi, Li
AU  - Yi L
FAU - Liu, Li
AU  - Liu L
FAU - Yuan, Liu-di
AU  - Yuan LD
FAU - Shi, Yan-feng
AU  - Shi YF
FAU - Xie, Wei
AU  - Xie W
LA  - chi
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Gan Zang Bing Za Zhi
JT  - Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of 
      hepatology
JID - 9710009
RN  - 0 (Membrane Proteins)
RN  - EC 1.1.1.- (AKR1B10 protein, human)
RN  - EC 1.1.1.- (Aldo-Keto Reductases)
RN  - EC 1.1.1.21 (Aldehyde Reductase)
RN  - EC 3.6.1.- (ADP-ribosylation factor related proteins)
RN  - EC 3.6.5.2 (ADP-Ribosylation Factors)
SB  - IM
MH  - ADP-Ribosylation Factors/*biosynthesis/genetics
MH  - Aldehyde Reductase/*biosynthesis/genetics
MH  - Aldo-Keto Reductases
MH  - Animals
MH  - Cloning, Molecular
MH  - Cricetinae
MH  - Cricetulus
MH  - Female
MH  - Gene Expression
MH  - Humans
MH  - Male
MH  - Membrane Proteins/*biosynthesis/genetics
MH  - Mice/*genetics
MH  - Pregnancy
MH  - Sequence Homology, Amino Acid
EDAT- 2004/08/27 05:00
MHDA- 2005/04/27 09:00
CRDT- 2004/08/27 05:00
PHST- 2004/08/27 05:00 [pubmed]
PHST- 2005/04/27 09:00 [medline]
PHST- 2004/08/27 05:00 [entrez]
PST - ppublish
SO  - Zhonghua Gan Zang Bing Za Zhi. 2004 Aug;12(8):463-6.