PMID- 15330506 OWN - NLM STAT- MEDLINE DCOM- 20050224 LR - 20061115 IS - 1433-6510 (Print) IS - 1433-6510 (Linking) VI - 50 IP - 7-8 DP - 2004 TI - FISH--a new noninvasive method for the diagnosis of urinary bladder carcinomas. PG - 395-402 AB - Urinary bladder carcinoma is one of the most frequent malignant tumour diseases. The frequency increases with advancing age. The knowledge increase about genetic changes in tumour cells opens the possibility of a new noninvasive diagnosis with the help of fluorescence in situ hybridization (FISH). Comparable data are obtained by application of different diagnostic methods (fluorescence in situ hybridization, urinary bladder cancer ELISA, urinary cytology, histopathology) at different times from 6 coincidentally selected patients (preoperation, biopsy material and postoperation). The FISH test proved to be a sensitive method and correlated with the histopathological data. FAU - Lubbe, Lieselotte AU - Lubbe L AD - Institute of Pathology, Carl-Thiem Clinic, Cottbus, Germany. FAU - Nowack, Rudolf AU - Nowack R FAU - May, Matthias AU - May M FAU - Ullmann, Kerstin AU - Ullmann K FAU - Gunia, Sven AU - Gunia S FAU - Kaufmann, Olaf AU - Kaufmann O FAU - Hakenberg, Oliver AU - Hakenberg O FAU - Muche, Joachim AU - Muche J FAU - Hoschke, Bernd AU - Hoschke B LA - eng PT - Journal Article PL - Germany TA - Clin Lab JT - Clinical laboratory JID - 9705611 SB - IM MH - Biopsy MH - Carcinoma, Transitional Cell/*diagnosis/pathology MH - Enzyme-Linked Immunosorbent Assay/methods MH - Humans MH - In Situ Hybridization, Fluorescence/*methods MH - Urinary Bladder Neoplasms/*diagnosis/pathology MH - Urine/cytology EDAT- 2004/08/28 05:00 MHDA- 2005/02/25 09:00 CRDT- 2004/08/28 05:00 PHST- 2004/08/28 05:00 [pubmed] PHST- 2005/02/25 09:00 [medline] PHST- 2004/08/28 05:00 [entrez] PST - ppublish SO - Clin Lab. 2004;50(7-8):395-402.