PMID- 15331792 OWN - NLM STAT- MEDLINE DCOM- 20050322 LR - 20220330 IS - 1524-4628 (Electronic) IS - 0039-2499 (Linking) VI - 35 IP - 10 DP - 2004 Oct TI - Prediction of stroke by self-measurement of blood pressure at home versus casual screening blood pressure measurement in relation to the Joint National Committee 7 classification: the Ohasama study. PG - 2356-61 AB - BACKGROUND AND PURPOSE: To compare the predictive power of self-measured home blood pressure (HBP) and casual blood pressure (CBP) for stroke risk in relation to the Joint National Committee 7 (JNC-7) classification. METHODS: HBP and CBP measurements were taken in 1702 subjects (> or =40 years) without a history of stroke, who were followed up for an average of 11 years. Subjects were classified into 4 groups on the basis of either HBP or CBP, according to the JNC-7 criteria: group 1 (HBP <115/75 mm Hg; CBP <120/80 mm Hg); group 2 (115/75< or =HBP<135/85 mm Hg; 120/80< or =CBP<140/90 mm Hg); group 3 (135/85< or =HBP<150/95 mm Hg; 140/90< or =CBP<160/100 mm Hg); and group 4 (HBP> or =150/95 mm Hg; CBP > or =160/100 mm Hg). Groups 2, 3, and 4 were further divided into 2 subgroups (a and b): those without and with cardiovascular disease risks, respectively. The risk of the first stroke in these groups was examined by the Cox hazards model adjusted for age and sex. RESULTS: The stroke risk in groups 3b and 4b (defined by HBP and CBP) was 2 to 5x higher than that in group 1 with significant differences. The risk in groups 2a, 3a, and even 4a was not significantly different from that in group 1 by the CBP-based classification, but the risk in group 4a was significantly higher than that in group 1 by the HBP-based classification, which also showed a stepwise increase in risk from groups 2a to 4a. CONCLUSIONS: The JNC-7 classification had a stronger predictive power using HBP-based classification compared with CBP-based classification, suggesting the usefulness of HBP in the management of hypertension. FAU - Asayama, Kei AU - Asayama K AD - Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan. FAU - Ohkubo, Takayoshi AU - Ohkubo T FAU - Kikuya, Masahiro AU - Kikuya M FAU - Metoki, Hirohito AU - Metoki H FAU - Hoshi, Haruhisa AU - Hoshi H FAU - Hashimoto, Junichiro AU - Hashimoto J FAU - Totsune, Kazuhito AU - Totsune K FAU - Satoh, Hiroshi AU - Satoh H FAU - Imai, Yutaka AU - Imai Y LA - eng PT - Journal Article DEP - 20040826 PL - United States TA - Stroke JT - Stroke JID - 0235266 SB - IM MH - Aged MH - *Blood Pressure Determination MH - Female MH - Humans MH - Hypertension/*diagnosis MH - Japan MH - Male MH - Middle Aged MH - Proportional Hazards Models MH - Risk Assessment MH - Stroke/*prevention & control EDAT- 2004/08/28 05:00 MHDA- 2005/03/23 09:00 CRDT- 2004/08/28 05:00 PHST- 2004/08/28 05:00 [pubmed] PHST- 2005/03/23 09:00 [medline] PHST- 2004/08/28 05:00 [entrez] AID - 01.STR.0000141679.42349.9f [pii] AID - 10.1161/01.STR.0000141679.42349.9f [doi] PST - ppublish SO - Stroke. 2004 Oct;35(10):2356-61. doi: 10.1161/01.STR.0000141679.42349.9f. Epub 2004 Aug 26.