PMID- 15332201
OWN - NLM
STAT- MEDLINE
DCOM- 20041221
LR  - 20151119
IS  - 0010-440X (Print)
IS  - 0010-440X (Linking)
VI  - 45
IP  - 5
DP  - 2004 Sep-Oct
TI  - Patients with obsessive-compulsive disorder and hoarding symptoms: a distinctive 
      clinical subtype?
PG  - 375-83
AB  - We investigated whether patients with obsessive-compulsive disorder (OCD) and 
      hoarding symptoms can be differentiated from their counterparts with other types 
      of obsessions and compulsions in terms of sociodemographic and clinical features. 
      Ninety-seven patients with OCD were assessed with a sociodemographic and clinical 
      questionnaire, the Structured Clinical Interview for DSM-IV (SCID-I), the 
      Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Beck Depression Inventory 
      (BDI), the Hamilton Rating Scale for Depression (HDRS), and the Global Assessment 
      of Functioning (GAF). Fifteen patients who reported hoarding symptoms in the 
      Y-BOCS checklist (15.6% of the total sample) were compared and contrasted with 82 
      patients without those symptoms using the Mann-Whitney U test for continuous 
      variables and the Pearson's goodness-of-fit chi-square test for categorical ones; 
      Fisher's exact test was employed when indicated. Hoarders were characterized by 
      (1) higher educational levels (chi(2) = 7.49; df = 2; P =.02); (2) earlier age at 
      onset (Z = -2.99; P =.003); (3) higher rates of symmetry obsessions (chi(2) = 
      7.03; df = 1; P =.01); (4) greater frequency of ordering (chi(2) = 10.08; df = 1; 
      P =.004); (5) rituals repetition (chi(2) = 4.42; df = 1; P =.03); (6) counting 
      compulsions (chi(2) = 5.92; df = 1; P =.02); and (7) significantly higher rates 
      of comorbidity with bipolar II disorder (chi(2) = 10.62; df = 1; P =.02) and (8) 
      with eating disorders (chi(2) = 7.42; df = 1; P =.02). In conclusion, patients 
      with OCD exhibiting hoarding feature a distinctive sociodemographic and clinical 
      profile. It remains to be investigated whether these phenotypical characteristics 
      are underlined by specific neurobiological mechanisms.
FAU - Fontenelle, Leonardo F
AU  - Fontenelle LF
AD  - Anxiety and Depression Research Program, Institute of Psychiatry of the Federal 
      University of Rio de Janiero, Brazil.
FAU - Mendlowicz, Mauro V
AU  - Mendlowicz MV
FAU - Soares, Isabela D
AU  - Soares ID
FAU - Versiani, Marcio
AU  - Versiani M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Compr Psychiatry
JT  - Comprehensive psychiatry
JID - 0372612
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Comorbidity
MH  - Compulsive Behavior/diagnosis/*epidemiology
MH  - Demography
MH  - Depressive Disorder, Major/diagnosis/epidemiology
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mood Disorders/epidemiology
MH  - Obsessive-Compulsive Disorder/diagnosis/*epidemiology
MH  - Personality Disorders/epidemiology
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
EDAT- 2004/08/28 05:00
MHDA- 2004/12/22 09:00
CRDT- 2004/08/28 05:00
PHST- 2004/08/28 05:00 [pubmed]
PHST- 2004/12/22 09:00 [medline]
PHST- 2004/08/28 05:00 [entrez]
AID - S0010440X04000410 [pii]
AID - 10.1016/j.comppsych.2004.03.005 [doi]
PST - ppublish
SO  - Compr Psychiatry. 2004 Sep-Oct;45(5):375-83. doi: 
      10.1016/j.comppsych.2004.03.005.