PMID- 15341979
OWN - NLM
STAT- MEDLINE
DCOM- 20041101
LR  - 20061115
IS  - 0959-8049 (Print)
IS  - 0959-8049 (Linking)
VI  - 40
IP  - 14
DP  - 2004 Sep
TI  - Psychological distress in women at increased risk for breast cancer: the role of 
      risk perception.
PG  - 2056-63
AB  - The magnetic resonance imaging screening (MRISC) study evaluates a surveillance 
      programme for women with a hereditary risk for breast cancer. The psychological 
      burden of surveillance in these women may depend on inaccurate risk perceptions. 
      To examine differences in risk perceptions between three predefined risk 
      categories and associations with psychological distress. BC-specific distress, 
      general distress, and RP (cognitive and affective) were assessed, two months 
      before a surveillance appointment. Cumulative lifetime risk (CLTR) of developing 
      breast cancer was trichotomised into: (1) CLTR of 60-85% (mutation carriers), (2) 
      CLTR of 30-50%, and (3) CLTR of 15-30%. In a total group of 351 women (mean age 
      40.5 years, range 21-63 years) the three risk categories significantly differed 
      in their accuracy of assessing cognitive risk perceptions. In category 1, 60% had 
      an accurate risk perceptions, in category 2, 43.7% and in category 3, 33.3%. 
      Overestimators reported significantly more breast cancer-specific distress. After 
      adding affective risk perception to the model, this effect disappeared. Affective 
      risk perceptions showed significant associations with breast cancer-specific and 
      general distress. Affective risk perception is a more important determinant for 
      psychological distress than cognitive risk perception. This knowledge should be 
      used during surveillance appointments in order to improve and individualise 
      support for these women.
FAU - van Dooren, Silvia
AU  - van Dooren S
AD  - Department of Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, The 
      Netherlands. s.vandooren@erasmusmc.nl
FAU - Rijnsburger, Adriana J
AU  - Rijnsburger AJ
FAU - Seynaeve, Caroline
AU  - Seynaeve C
FAU - Duivenvoorden, Hugo J
AU  - Duivenvoorden HJ
FAU - Essink-Bot, Marie-Louise
AU  - Essink-Bot ML
FAU - Tilanus-Linthorst, Madeleine M A
AU  - Tilanus-Linthorst MM
FAU - de Koning, Harry J
AU  - de Koning HJ
FAU - Tibben, Aad
AU  - Tibben A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur J Cancer
JT  - European journal of cancer (Oxford, England : 1990)
JID - 9005373
SB  - IM
MH  - Adult
MH  - Breast Neoplasms/genetics/prevention & control/*psychology
MH  - Female
MH  - Genes, BRCA1
MH  - Genes, BRCA2
MH  - Genetic Counseling
MH  - Humans
MH  - Longitudinal Studies
MH  - Middle Aged
MH  - Mutation/genetics
MH  - Perception
MH  - Risk Assessment
MH  - Risk Factors
MH  - Stress, Psychological/*etiology
EDAT- 2004/09/03 05:00
MHDA- 2004/11/02 09:00
CRDT- 2004/09/03 05:00
PHST- 2004/02/05 00:00 [received]
PHST- 2004/05/05 00:00 [revised]
PHST- 2004/05/06 00:00 [accepted]
PHST- 2004/09/03 05:00 [pubmed]
PHST- 2004/11/02 09:00 [medline]
PHST- 2004/09/03 05:00 [entrez]
AID - S0959804904004101 [pii]
AID - 10.1016/j.ejca.2004.05.004 [doi]
PST - ppublish
SO  - Eur J Cancer. 2004 Sep;40(14):2056-63. doi: 10.1016/j.ejca.2004.05.004.