PMID- 15347300 OWN - NLM STAT- MEDLINE DCOM- 20050215 LR - 20131121 IS - 1083-4389 (Print) IS - 1083-4389 (Linking) VI - 9 Suppl 1 DP - 2004 TI - Diagnosis of Helicobacter pylori infection. PG - 7-14 AB - While there are some attempts to improve culture of Helicobacter pylori, molecular methods have been the main focus of this interest. Their main application concerns the development of rapid tests also allowing the determination of bacterial resistance, i.e. real-time polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH), or to genotype the strains. Attempts to improve, simplify or explain the discrepancies of urea breath test results have been made and new generation of stool antigen test with monoclonal antibodies either using the standard ELISA format or rapid immunoenzymatic detection have confirmed their value. With regard to serology, studies have mainly focused on the distinction of infections with more pathogenic strains and the ability to diagnose atrophic gastritis with the Gastropanel. FAU - Makristathis, Athanasios AU - Makristathis A AD - Department of Clinical Microbiology, Institute of Hygiene and Medical Microbiology, Medical University Vienna, Vienna, Austria. FAU - Hirschl, Alexander M AU - Hirschl AM FAU - Lehours, Philippe AU - Lehours P FAU - Megraud, Francis AU - Megraud F LA - eng PT - Journal Article PT - Review PL - England TA - Helicobacter JT - Helicobacter JID - 9605411 RN - 8W8T17847W (Urea) SB - IM MH - Breath Tests MH - Culture Techniques MH - Drug Resistance, Bacterial/genetics MH - Feces/microbiology MH - Genotype MH - Helicobacter Infections/*diagnosis MH - Helicobacter pylori/genetics/growth & development/*isolation & purification MH - Humans MH - Molecular Diagnostic Techniques/methods MH - Polymerase Chain Reaction MH - Serologic Tests MH - Urea/metabolism RF - 76 EDAT- 2004/09/07 05:00 MHDA- 2005/02/16 09:00 CRDT- 2004/09/07 05:00 PHST- 2004/09/07 05:00 [pubmed] PHST- 2005/02/16 09:00 [medline] PHST- 2004/09/07 05:00 [entrez] AID - HEL254 [pii] AID - 10.1111/j.1083-4389.2004.00254.x [doi] PST - ppublish SO - Helicobacter. 2004;9 Suppl 1:7-14. doi: 10.1111/j.1083-4389.2004.00254.x.