PMID- 15367217
OWN - NLM
STAT- MEDLINE
DCOM- 20050308
LR  - 20230124
IS  - 1600-6135 (Print)
IS  - 1600-6135 (Linking)
VI  - 4
IP  - 10
DP  - 2004 Oct
TI  - Donor kidney exchanges.
PG  - 1628-34
AB  - Kidney transplantation from live donors achieves an excellent outcome regardless 
      of human leukocyte antigen (HLA) mismatch. This development has expanded the 
      opportunity of kidney transplantation from unrelated live donors. Nevertheless, 
      the hazard of hyperacute rejection has usually precluded the transplantation of a 
      kidney from a live donor to a potential recipient who is incompatible by ABO 
      blood type or HLA antibody crossmatch reactivity. Region 1 of the United Network 
      for Organ Sharing (UNOS) has devised an alternative system of kidney 
      transplantation that would enable either a simultaneous exchange between live 
      donors (a paired exchange), or a live donor/deceased donor exchange to 
      incompatible recipients who are waiting on the list (a live donor/list exchange). 
      This Regional system of exchange has derived the benefit of live donation, 
      avoided the risk of ABO or crossmatch incompatibility, and yielded an additional 
      donor source for patients awaiting a deceased donor kidney. Despite the initial 
      disadvantage to the list of patients awaiting an O blood type kidney, as every 
      paired exchange transplant removes a patient from the waiting list, it also 
      avoids the incompatible recipient from eventually having to go on the list. Thus, 
      this approach also increases access to deceased donor kidneys for the remaining 
      candidates on the list.
FAU - Delmonico, Francis L
AU  - Delmonico FL
AD  - New England Organ Bank, Newton, MA, USA. francis_delmonico@neob.org
FAU - Morrissey, Paul E
AU  - Morrissey PE
FAU - Lipkowitz, George S
AU  - Lipkowitz GS
FAU - Stoff, Jeffrey S
AU  - Stoff JS
FAU - Himmelfarb, Jonathan
AU  - Himmelfarb J
FAU - Harmon, William
AU  - Harmon W
FAU - Pavlakis, Martha
AU  - Pavlakis M
FAU - Mah, Helen
AU  - Mah H
FAU - Goguen, Jane
AU  - Goguen J
FAU - Luskin, Richard
AU  - Luskin R
FAU - Milford, Edgar
AU  - Milford E
FAU - Basadonna, Giacomo
AU  - Basadonna G
FAU - Chobanian, Michael
AU  - Chobanian M
FAU - Bouthot, Beth
AU  - Bouthot B
FAU - Lorber, Marc
AU  - Lorber M
FAU - Rohrer, Richard J
AU  - Rohrer RJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Transplant
JT  - American journal of transplantation : official journal of the American Society of 
      Transplantation and the American Society of Transplant Surgeons
JID - 100968638
SB  - IM
CIN - Am J Transplant. 2004 Oct;4(10):1553-4. PMID: 15367208
CIN - J Urol. 2005 Apr;173(4):1430. PMID: 15758820
MH  - Cadaver
MH  - Humans
MH  - *Kidney Transplantation
MH  - Living Donors
MH  - New England
MH  - *Tissue Donors
MH  - *Tissue and Organ Procurement
EDAT- 2004/09/16 05:00
MHDA- 2005/03/09 09:00
CRDT- 2004/09/16 05:00
PHST- 2004/09/16 05:00 [pubmed]
PHST- 2005/03/09 09:00 [medline]
PHST- 2004/09/16 05:00 [entrez]
AID - S1600-6135(22)07999-0 [pii]
AID - 10.1111/j.1600-6143.2004.00572.x [doi]
PST - ppublish
SO  - Am J Transplant. 2004 Oct;4(10):1628-34. doi: 10.1111/j.1600-6143.2004.00572.x.