PMID- 15367501
OWN - NLM
STAT- MEDLINE
DCOM- 20041004
LR  - 20181113
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Print)
IS  - 1355-6037 (Linking)
VI  - 90
IP  - 10
DP  - 2004 Oct
TI  - Biochemical markers of myocyte injury in heart failure.
PG  - 1110-3
AB  - This review discusses the role of biochemical markers of myocyte injury in 
      patients with chronic congestive heart failure. Heart specific assays have been 
      developed for the measurement of cardiac troponin T (cTnT), cardiac troponin I 
      (cTnI), heart type fatty acid binding protein (H-FABP), and myosin light chain 1 
      (MLC-1). Concentrations of these biochemical markers increase in the absence of 
      ischaemic events in the subset of patients with heart failure whose long term 
      outcomes are most adverse. The markers are easy to measure serially and it is 
      therefore easy to follow patients without inter-observer variability. The serial 
      clinical use of these markers, separately or in combination, will sharpen our 
      understanding of the state of heart failure.
FAU - Sato, Y
AU  - Sato Y
AD  - Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto 
      University, 54 Kawaracho Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. 
      cardioys@kuhp.kyoto-u.ac.jp
FAU - Kita, T
AU  - Kita T
FAU - Takatsu, Y
AU  - Takatsu Y
FAU - Kimura, T
AU  - Kimura T
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
RN  - 0 (Biomarkers)
RN  - 0 (Carrier Proteins)
RN  - 0 (Fatty Acid-Binding Proteins)
RN  - 0 (Myosin Light Chains)
RN  - 0 (Troponin I)
RN  - 0 (Troponin T)
RN  - 0 (myosin light chain I)
SB  - IM
MH  - Biomarkers/blood
MH  - Carrier Proteins/blood
MH  - Fatty Acid-Binding Proteins
MH  - Heart Failure/blood/*pathology
MH  - Humans
MH  - Myocytes, Cardiac/*pathology
MH  - Myosin Light Chains/blood
MH  - Prognosis
MH  - Troponin I/*blood
MH  - Troponin T/*blood
PMC - PMC1768497
EDAT- 2004/09/16 05:00
MHDA- 2004/10/05 09:00
PMCR- 2007/10/01
CRDT- 2004/09/16 05:00
PHST- 2004/09/16 05:00 [pubmed]
PHST- 2004/10/05 09:00 [medline]
PHST- 2004/09/16 05:00 [entrez]
PHST- 2007/10/01 00:00 [pmc-release]
AID - 90/10/1110 [pii]
AID - 0901110 [pii]
AID - 10.1136/hrt.2003.023895 [doi]
PST - ppublish
SO  - Heart. 2004 Oct;90(10):1110-3. doi: 10.1136/hrt.2003.023895.