PMID- 15368514
OWN - NLM
STAT- MEDLINE
DCOM- 20041104
LR  - 20041117
IS  - 0146-6615 (Print)
IS  - 0146-6615 (Linking)
VI  - 74
IP  - 3
DP  - 2004 Nov
TI  - Correlates of human herpes virus-8 and herpes simplex virus type 2 infections in 
      Northern Cameroon.
PG  - 467-72
AB  - The association between sexual activity and human herpes virus-8 (HHV-8) 
      infection has been established, but the mode of acquisition is still unclear. 
      Blood samples from 238 individuals from Northern Cameroon were tested to evaluate 
      the incidence of herpes simplex virus-2 (HSV-2), human immunodeficiency virus 
      (HIV), Treponema pallidum, and HHV-8 infections and to identify their possible 
      association. The presence of HSV-2 antibodies was associated significantly with 
      gender, age, and HIV, HHV-8 antilatent, and T. pallidum antibodies, but not with 
      HHV-8 antilytic antibodies. In a multivariate model older age, female gender, 
      seropositivity for HIV, for HHV-8 latent antigens and for T. pallidum were 
      associated independently with seropositivity for HSV-2. HSV-2-seropositive 
      individuals had significantly higher titers of antibodies to both lytic (P = 
      0.019) and latent (P = 0.021) HHV-8 antigens. These results suggest that HSV-2 
      infection can contribute to sexual transmission of HHV-8 infection.
FAU - Volpi, A
AU  - Volpi A
AD  - Department of Public Health, University Tor Vergata, Rome, Italy. 
      volpi@uniroma2.it
FAU - Sarmati, L
AU  - Sarmati L
FAU - Suligoi, B
AU  - Suligoi B
FAU - Montano, M
AU  - Montano M
FAU - Rezza, G
AU  - Rezza G
FAU - Andreoni, M
AU  - Andreoni M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Med Virol
JT  - Journal of medical virology
JID - 7705876
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antibodies, Viral/blood
MH  - Cameroon/epidemiology
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - HIV Infections/complications/epidemiology
MH  - Herpes Simplex/complications/*epidemiology/immunology
MH  - Herpesviridae Infections/complications/*epidemiology/immunology
MH  - *Herpesvirus 2, Human/immunology
MH  - *Herpesvirus 8, Human/immunology
MH  - Humans
MH  - Male
MH  - Seroepidemiologic Studies
MH  - Syphilis/complications/epidemiology
EDAT- 2004/09/16 05:00
MHDA- 2004/11/05 09:00
CRDT- 2004/09/16 05:00
PHST- 2004/09/16 05:00 [pubmed]
PHST- 2004/11/05 09:00 [medline]
PHST- 2004/09/16 05:00 [entrez]
AID - 10.1002/jmv.20200 [doi]
PST - ppublish
SO  - J Med Virol. 2004 Nov;74(3):467-72. doi: 10.1002/jmv.20200.