PMID- 15375617
OWN - NLM
STAT- MEDLINE
DCOM- 20050328
LR  - 20061115
IS  - 1107-3756 (Print)
IS  - 1107-3756 (Linking)
VI  - 14
IP  - 4
DP  - 2004 Oct
TI  - Cytogenetic characterization of seven human cancer cell lines by combining G- and 
      R-banding, M-FISH, CGH and chromosome- and locus-specific FISH.
PG  - 483-95
AB  - Leukemia cell lines K562, KG1a, U937, HL60, Jurkat and solid tumor cell lines 
      A549 and M4Beu are widely used in studies of cell cycle, apoptosis and adhesion 
      mechanisms in cancer cells. Although the K562 and U937 cell lines were previously 
      subjected to a detailed cytogenetic characterization, only a few molecular 
      cytogenetic investigations have been performed on the other five cell lines. We 
      combined several molecular cytogenetic techniques, such as fluorescence in situ 
      hybridization (FISH), multicolor FISH (M-FISH), and comparative genomic 
      hybridization (CGH) to demonstrate the precise genetic aberrations in tumor 
      genomes of these seven cell lines. This information may be useful for multiple 
      studies on these cell lines, providing a genetic basis for the interpretations of 
      experimental findings.
FAU - Cottier, Michele
AU  - Cottier M
AD  - Laboratoire d'Histologie-Embryologie-Cytogenetique, Faculte de Medecine J. 
      Lisfranc, Hopital Nord, CHU de Saint-Etienne, 42055 Saint-Etienne Cedex 2, 
      France.
FAU - Tchirkov, Andrei
AU  - Tchirkov A
FAU - Perissel, Bernard
AU  - Perissel B
FAU - Giollant, Michel
AU  - Giollant M
FAU - Campos, Lydia
AU  - Campos L
FAU - Vago, Philippe
AU  - Vago P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Greece
TA  - Int J Mol Med
JT  - International journal of molecular medicine
JID - 9810955
RN  - 0 (DNA, Neoplasm)
SB  - IM
MH  - Cell Line, Tumor
MH  - Chromosome Banding
MH  - Chromosomes, Human/*genetics
MH  - Cytogenetic Analysis/*methods
MH  - DNA, Neoplasm/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - K562 Cells
MH  - Karyotyping
MH  - Neoplasms/*genetics/*pathology
MH  - Nucleic Acid Hybridization
MH  - U937 Cells
EDAT- 2004/09/18 05:00
MHDA- 2005/03/29 09:00
CRDT- 2004/09/18 05:00
PHST- 2004/09/18 05:00 [pubmed]
PHST- 2005/03/29 09:00 [medline]
PHST- 2004/09/18 05:00 [entrez]
PST - ppublish
SO  - Int J Mol Med. 2004 Oct;14(4):483-95.