PMID- 1544729
OWN - NLM
STAT- MEDLINE
DCOM- 19920416
LR  - 20061115
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 13
IP  - 1
DP  - 1992 Jan
TI  - The effect of Alpine mountaineering on acute erythrocyte hemolysis.
PG  - 31-5
AB  - The purpose of this study was to determine whether erythrocyte hemolysis occurs 
      during a mountain ascent over snow and ice to 3285 meters. Data were collected 
      from six experienced recreational mountaineers, 2 females and 4 males, who 
      participated in a six-day ice climbing seminar and peak ascent in the North 
      Cascades mountain range of the United States. Blood samples were collected from 
      an antecubital vein at sea level (S1), in a base camp at 1515 m prior to the 
      summit ascent (S2), on the summit at 3285 m after 6.5 hours of climbing (S3), at 
      base camp immediately after the descent (S4), and at sea level following a trail 
      descent from the base camp (S5). Whole blood samples were chilled and analyzed 
      for complete blood count including hemoglobin (Hb) concentration, hematocrit 
      (Hct), and white blood cell count (WBC). Serum was frozen and later analyzed for 
      serum haptoglobin (Hapt). No significant changes were found for Hct and Hb among 
      the samples. Mean (+/- SEM) Hapt values were 125 (+/- 28), 113 (+/- 25), 100 (+/- 
      18), 103 (+/- 32), and 109 (+/- 23) mg.dl-1 for S1 through S5, respectively. No 
      significant differences were found among the Hapt values. Plasma volume changes 
      (% PVC) were calculated from Hct and Hb. Mean estimated % PVC were -4.16 (+/- 
      1.55), -2.54 (+/- 3.93), 7.46 (+/- 4.86), and 4.80 (+/- 3.49) percent between S1 
      and S2, S2 and S3, S3 and S4, and S4 and S5, respectively. Total body haptoglobin 
      (TBH) was estimated from Hapt and % PVC in an attempt to correct for the plasma 
      volume change effect on haptoglobin concentration.(ABSTRACT TRUNCATED AT 250 
      WORDS)
FAU - Martin, D T
AU  - Martin DT
AD  - Exercise Science Laboratory, Northern Michigan University, Marquette 49855.
FAU - Watts, P B
AU  - Watts PB
FAU - Newbury, V S
AU  - Newbury VS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Haptoglobins)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Cell Count
MH  - Female
MH  - Haptoglobins/analysis
MH  - Hematocrit
MH  - *Hemolysis
MH  - Humans
MH  - Male
MH  - *Mountaineering
MH  - Plasma Volume
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
AID - 10.1055/s-2007-1021230 [doi]
PST - ppublish
SO  - Int J Sports Med. 1992 Jan;13(1):31-5. doi: 10.1055/s-2007-1021230.