PMID- 15451085
OWN - NLM
STAT- MEDLINE
DCOM- 20041221
LR  - 20040928
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 145
IP  - 2-3
DP  - 2004 Oct 29
TI  - Amphetamines in washed hair of demonstrated users and workplace subjects.
PG  - 137-42
AB  - In a study of volunteer subjects from drug rehabilitation programs, 
      methamphetamine and amphetamine levels were determined in the hair of 40 subjects 
      who had produced MS-confirmed methamphetamine-positive urine results. The samples 
      were tested by radioimmunoassay and analyzed by LC/MS/MS after being washed with 
      the 3.75-h wash procedure developed by this laboratory. In addition, results of 
      non-user and workplace samples are presented. In workplace samples, levels of 
      methamphetamine, amphetamine, methylenedioxy-methamphetamine (MDMA), and 
      methylenedioxyamphetamine (MDA), are reported. The range of methamphetamine 
      levels in the clinical samples (170-34,400 pg/mg hair) was not different from the 
      workplace population (from less than the cutoff of 500 pg/mg to >20,000 pg/mg 
      hair), but the workplace population had a lower percentage of high levels of 
      drug. Amphetamine levels were found to vary widely in both populations, at all 
      levels of methamphetamine. In the clinical population, no samples were positive 
      for MDMA; in MDMA-positive workplace samples, the levels ranged from below the 
      cutoff of 500 to >20,000 pg/mg, with MDA levels varying widely, similar to 
      amphetamine levels in methamphetamine-positive samples.
FAU - Cairns, Thomas
AU  - Cairns T
AD  - Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA.
FAU - Hill, Virginia
AU  - Hill V
FAU - Schaffer, Michael
AU  - Schaffer M
FAU - Thistle, William
AU  - Thistle W
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Amphetamines)
RN  - 0 (Central Nervous System Stimulants)
SB  - IM
MH  - Adult
MH  - Amphetamine-Related Disorders/diagnosis
MH  - Amphetamines/*analysis
MH  - Central Nervous System Stimulants/*analysis
MH  - Chromatography, Liquid
MH  - *Decontamination
MH  - Female
MH  - Forensic Medicine/methods
MH  - Hair/*chemistry
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radioimmunoassay
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Substance Abuse Detection/methods
MH  - Workplace
EDAT- 2004/09/29 05:00
MHDA- 2004/12/22 09:00
CRDT- 2004/09/29 05:00
PHST- 2004/09/29 05:00 [pubmed]
PHST- 2004/12/22 09:00 [medline]
PHST- 2004/09/29 05:00 [entrez]
AID - S0379073804002439 [pii]
AID - 10.1016/j.forsciint.2004.04.028 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2004 Oct 29;145(2-3):137-42. doi: 
      10.1016/j.forsciint.2004.04.028.