PMID- 15451093
OWN - NLM
STAT- MEDLINE
DCOM- 20041221
LR  - 20061115
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 145
IP  - 2-3
DP  - 2004 Oct 29
TI  - Progress in pesticide and POPs hair analysis for the assessment of exposure.
PG  - 195-9
AB  - The present paper reviews the work that has been done in the field of pesticide 
      and persistent organic pollutants (POPs) hair analysis during the last 15 years. 
      It summarizes the compounds of interest, the methods of analyte extraction from 
      the hair matrix, the analytical techniques employed and the results obtained. The 
      most widely studied POPs are the polychlorinated dibenzodioxins (PCDDs), the 
      dibenzofurans (PCDFs) the co-planar biphenyls (co-PCBs) and total biphenyls 
      (PCBs). The most widely studied pesticides are the organochlorine ones, like the 
      hexachlorocyclohexanes and the DDTs, which nowadays are only found as 
      environmental pollutants, some organophosphates, selected pyrethroids and the 
      carbamate methomyl. The most widely applied technique was gas chromatography (GC) 
      coupled to mass spectrometry (MS). Other detectors like the ECD in the case of 
      organochlorine analysis and the NPD in the case of organophosphate analysis were 
      also used. The presented data concern human and animal studies. The levels of 
      DDTs detected in hair were between 19 and 400 ng/g, of co-PCBs 0.27 and 0.45 
      ng/g, of total PCBs 5-13 ng/g of PCDDs and PCDFs 0.1-10 pg/g of lindane 20-400 
      ng/g of HCHs 14-40 ng/g of diazinon 110-520 ng/g and of methomyl 900-1800 ng/g. 
      These results strongly support the possibility of using hair as a suitable 
      indicator for the assessment of long-term exposure to POPs and pesticides.
FAU - Tsatsakis, Aristidis
AU  - Tsatsakis A
AD  - Department of Medicine, Centre of Toxicological Sciences and Research, School of 
      Health Sciences, University of Crete, Voutes Heraklion, 71409 Crete, Greece. 
      aris@med.uoc.gr
FAU - Tutudaki, Maria
AU  - Tutudaki M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
SB  - IM
MH  - Animals
MH  - Environmental Exposure/*analysis
MH  - Forensic Medicine/methods
MH  - Gas Chromatography-Mass Spectrometry
MH  - Hair/*chemistry
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*analysis
MH  - Pesticides/*analysis
RF  - 17
EDAT- 2004/09/29 05:00
MHDA- 2004/12/22 09:00
CRDT- 2004/09/29 05:00
PHST- 2004/09/29 05:00 [pubmed]
PHST- 2004/12/22 09:00 [medline]
PHST- 2004/09/29 05:00 [entrez]
AID - S0379073804002518 [pii]
AID - 10.1016/j.forsciint.2004.04.036 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2004 Oct 29;145(2-3):195-9. doi: 
      10.1016/j.forsciint.2004.04.036.