PMID- 15456989
OWN - NLM
STAT- MEDLINE
DCOM- 20050207
LR  - 20091103
IS  - 0957-5243 (Print)
IS  - 0957-5243 (Linking)
VI  - 15
IP  - 8
DP  - 2004 Oct
TI  - Occupation and bladder cancer risk in a population-based case-control study in 
      New Hampshire.
PG  - 759-69
AB  - OBJECTIVE: To identify occupations with excess bladder cancer risk in New 
      Hampshire, where bladder cancer mortality rates have been elevated for decades. 
      METHODS: Lifetime occupational histories were obtained from interviews with 424 
      cases and 645 controls in a population-based case-control study. Unconditional 
      logistic regression models were used to estimate odds ratios (Ors) and 95% 
      confidence intervals (CI) for each occupation, adjusted for age and smoking. 
      Analyses by duration of employment were carried out and interactions with smoking 
      were examined. RESULTS: Male tractor-trailer truck drivers had an elevated risk 
      for bladder cancer (OR = 2.4, CI = 1.4-4.1), with a significant positive trend in 
      risk with increasing duration of employment (P (trend) = 0.0003). Male 
      metal/plastic processing machine operators also had a significant excess (OR = 
      4.9, CI = 1.6-15.1), attributable mainly to molding/casting machine operators (OR 
      = 16.6, CI = 2.1-131). Elevated risk was also observed for male fabricators, 
      assemblers, and hand workers (OR = 1.8, CI = 1.0-3.4). Women in certain sales 
      occupations (sales clerks, counter clerks, and cashiers) had a significant excess 
      risk (OR = 2.2, CI = 1.3-3.9) and a significant trend with duration of employment 
      (P (trend) = 0.016), as did female health service workers (OR = 4.1, CI = 
      1.6-10.7; P (trend) = 0.014). There was a positive interaction between smoking 
      and employment as a health service worker (p = 0.036). CONCLUSIONS: These 
      findings are generally consistent with previous studies. Elevated risks for male 
      molding/casting machine operators, female salesworkers, and female health service 
      workers, especially those with a history of smoking, require further 
      investigation.
FAU - Colt, Joanne S
AU  - Colt JS
AD  - Division of Cancer Epidemiology and Genetics, National Cancer Institute, National 
      Institutes of Health, Department of Health and Human Services, Occupational And 
      Environmental Epidemiology Branch, Bethesda, MD 20892-7240, USA. 
      coltj@mail.nih.gov
FAU - Baris, Dalsu
AU  - Baris D
FAU - Stewart, Patricia
AU  - Stewart P
FAU - Schned, Alan R
AU  - Schned AR
FAU - Heaney, John A
AU  - Heaney JA
FAU - Mott, Leila A
AU  - Mott LA
FAU - Silverman, Debra
AU  - Silverman D
FAU - Karagas, Margaret
AU  - Karagas M
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Cancer Causes Control
JT  - Cancer causes & control : CCC
JID - 9100846
SB  - IM
MH  - Adult
MH  - Aged
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - New Hampshire/epidemiology
MH  - *Occupational Exposure
MH  - *Occupations
MH  - Registries/*statistics & numerical data
MH  - Risk Factors
MH  - Sex Factors
MH  - Urinary Bladder Neoplasms/*epidemiology/*etiology
EDAT- 2004/10/01 05:00
MHDA- 2005/02/08 09:00
CRDT- 2004/10/01 05:00
PHST- 2004/10/01 05:00 [pubmed]
PHST- 2005/02/08 09:00 [medline]
PHST- 2004/10/01 05:00 [entrez]
AID - 5278700 [pii]
AID - 10.1023/B:CACO.0000043426.28741.a2 [doi]
PST - ppublish
SO  - Cancer Causes Control. 2004 Oct;15(8):759-69. doi: 
      10.1023/B:CACO.0000043426.28741.a2.