PMID- 15458727
OWN - NLM
STAT- MEDLINE
DCOM- 20050127
LR  - 20151119
IS  - 1570-0232 (Print)
IS  - 1570-0232 (Linking)
VI  - 811
IP  - 1
DP  - 2004 Nov 5
TI  - 3-Methoxytyramine as an indicator of dopaminergic manipulation in the equine 
      athlete.
PG  - 93-101
AB  - The influence of sampling variables on the concentration of the dopamine 
      metabolites 3-methoxytyramine (3MT), dihydroxyphenylacetic acid (DOPAC) and 
      homovanilic acid (HVA) was examined in equine urine. A logarithmic transformation 
      of the data for all horses gave distribution which approximated the normal 
      distributions for each metabolite. The mean urinary concentration of 3 MT in 
      horses was 214 ng/mL and the application of a threshold with a probability of 1 
      in 10,000 gave an actionable level of 4 microg/mL. Environmental variables were 
      not forensically significant in determining the population distribution. HVA was 
      not found to be a reliable indicator of dopamine or levodopa administration.
FAU - Wynne, Paul M
AU  - Wynne PM
AD  - Racing Analytical Services Limited, 400 Epsom Road, Flemington, Vic. 3031, 
      Australia. pwynne@sge.com
FAU - Vine, John H
AU  - Vine JH
FAU - Amiet, R Gary
AU  - Amiet RG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - JCH2767EDP (3-methoxytyramine)
RN  - VTD58H1Z2X (Dopamine)
SB  - IM
MH  - Animals
MH  - Dopamine/*administration & dosage/*analogs & derivatives/*urine
MH  - *Doping in Sports
MH  - Horses
EDAT- 2004/10/02 05:00
MHDA- 2005/01/28 09:00
CRDT- 2004/10/02 05:00
PHST- 2003/11/20 00:00 [received]
PHST- 2004/03/25 00:00 [accepted]
PHST- 2004/10/02 05:00 [pubmed]
PHST- 2005/01/28 09:00 [medline]
PHST- 2004/10/02 05:00 [entrez]
AID - S1570-0232(04)00632-4 [pii]
AID - 10.1016/j.jchromb.2004.03.078 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Nov 5;811(1):93-101. doi: 
      10.1016/j.jchromb.2004.03.078.