PMID- 15460162
OWN - NLM
STAT- MEDLINE
DCOM- 20041207
LR  - 20191109
IS  - 0926-5287 (Print)
IS  - 0926-5287 (Linking)
VI  - 44
IP  - 3
DP  - 2004 May-Jun
TI  - Response of hexokinase enzymes and the insulin system to dietary carbohydrates in 
      the common carp, Cyprinus carpio.
PG  - 233-42
AB  - The response of the common carp to diets with varying amounts of digestible 
      starch, provided either as pea meal (LP, HP, 30 and 46% peas, respectively) or as 
      cereal (LW, HW, 30 and 46% wheat, respectively), was studied and compared with 
      the response to a carbohydrate-free protein-rich diet (CF). Here we focused on 
      the utilisation of dietary carbohydrates by examining the relationship between 
      dietary starch intake, hepatic hexokinase activities, circulating insulin and 
      muscle insulin receptor system. Plasma glucose concentration and hepatic high Km 
      hexokinase (glucokinase, GK) activity were not affected by the content of 
      digestible starch, but 6 h after feeding enzyme activity was higher in the fish 
      fed carbohydrate diets. Similarly, low Km hexokinase (HK) activity was also 
      higher in the fish 24 h after feeding. Fat gain and protein retention were 
      significantly improved by increased digestible starch intake, especially in the 
      HP group, which in turn, presented the highest plasma insulin levels. Glycogen 
      stores were moderately increased by the ingestion of digestible starch. The 
      number of insulin receptors was greater in the CF group than in fish on 
      carbohydrates, except the HP group. Our results confirmed that the common carp 
      uses dietary carbohydrates efficiently, especially when there are provided by 
      peas. This efficiency might be related to the enhanced response of postprandial 
      insulin observed in the HP group.
FAU - Capilla, Encarnacion
AU  - Capilla E
AD  - Departament de Fisiologia, Facultat de Biologia, Universitat de Barcelona, 08028 
      Barcelona, Spain.
FAU - Medale, Francoise
AU  - Medale F
FAU - Panserat, Stephane
AU  - Panserat S
FAU - Vachot, Christiane
AU  - Vachot C
FAU - Rema, Paulo
AU  - Rema P
FAU - Gomes, Emidio
AU  - Gomes E
FAU - Kaushik, Sadasivam
AU  - Kaushik S
FAU - Navarro, Isabel
AU  - Navarro I
FAU - Gutierrez, Joaquim
AU  - Gutierrez J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - France
TA  - Reprod Nutr Dev
JT  - Reproduction, nutrition, development
JID - 8913069
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - 9005-25-8 (Starch)
RN  - 9005-79-2 (Glycogen)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.10.1 (Receptor, Insulin)
SB  - IM
MH  - Animals
MH  - Blood Glucose/analysis
MH  - Carps/growth & development/*physiology
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Glycogen/analysis
MH  - Hexokinase/*metabolism
MH  - Insulin/*blood
MH  - Liver/chemistry/enzymology
MH  - Muscles/chemistry
MH  - Receptor, Insulin/analysis/physiology
MH  - Starch/administration & dosage
EDAT- 2004/10/06 09:00
MHDA- 2004/12/16 09:00
CRDT- 2004/10/06 09:00
PHST- 2004/10/06 09:00 [pubmed]
PHST- 2004/12/16 09:00 [medline]
PHST- 2004/10/06 09:00 [entrez]
AID - 10.1051/rnd:2004027 [doi]
PST - ppublish
SO  - Reprod Nutr Dev. 2004 May-Jun;44(3):233-42. doi: 10.1051/rnd:2004027.