PMID- 15471277
OWN - NLM
STAT- MEDLINE
DCOM- 20041202
LR  - 20191026
IS  - 0387-821X (Print)
IS  - 0387-821X (Linking)
VI  - 26
IP  - 3
DP  - 2004 Sep 1
TI  - Successful thromboendarterectomy for severe chronic thromboembolic pulmonary 
      hypertension caused by primary antiphospholipid syndrome.
PG  - 287-94
AB  - Pulmonary hypertension is one of the lethal complications in the antiphospholipid 
      syndrome due to chronic recurrence of embolism or thrombosis. We experienced a 
      19-year-old man suffering from severe chronic thromboembolic pulmonary 
      hypertension (CTEPH) caused by primary antiphospholipid syndrome. According to 
      the guideline, pulmonary thromboendarterectomy was decided on after combined 
      therapy with warfarin, beraprost and oxygen inhalation had not been effective 
      enough to improve severe CTEPH. By an operation, the mean pressure of the 
      pulmonary artery was decreased from 50 mmHg to 16 mmHg, while his New York Heart 
      Association (NYHA) functional class classification significantly improved from 
      class III to class I. We concluded that pulmonary thromboendarterectomy could 
      dramatically improve hemodynamic indices, NYHA functional status and quality of 
      life in patients with CTEPH.
FAU - Kamezaki, Fumihiko
AU  - Kamezaki F
AD  - Second Department of Internal Medicine, School of Medicine, University of 
      Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu 807-8555, 
      Japan.
FAU - Tasaki, Hiromi
AU  - Tasaki H
FAU - Yamanaka, Asuka
AU  - Yamanaka A
FAU - Morishita, Tsuyoshi
AU  - Morishita T
FAU - Hirakawa, Noriko
AU  - Hirakawa N
FAU - Yamashita, Kazuhito
AU  - Yamashita K
FAU - Okazaki, Masahiro
AU  - Okazaki M
FAU - Nakashima, Yasuhide
AU  - Nakashima Y
FAU - Nakanishi, Norifumi
AU  - Nakanishi N
FAU - Ogino, Hitoshi
AU  - Ogino H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - J UOEH
JT  - Journal of UOEH
JID - 7909645
SB  - IM
MH  - Adult
MH  - Antiphospholipid Syndrome/*complications
MH  - Chronic Disease
MH  - *Endarterectomy
MH  - Humans
MH  - Hypertension, Pulmonary/*etiology/*therapy
MH  - Male
MH  - Pulmonary Embolism/*etiology/*therapy
MH  - Severity of Illness Index
MH  - Treatment Outcome
EDAT- 2004/10/09 09:00
MHDA- 2004/12/16 09:00
CRDT- 2004/10/09 09:00
PHST- 2004/10/09 09:00 [pubmed]
PHST- 2004/12/16 09:00 [medline]
PHST- 2004/10/09 09:00 [entrez]
AID - 10.7888/juoeh.26.287 [doi]
PST - ppublish
SO  - J UOEH. 2004 Sep 1;26(3):287-94. doi: 10.7888/juoeh.26.287.