PMID- 15472993
OWN - NLM
STAT- MEDLINE
DCOM- 20050505
LR  - 20200930
IS  - 1552-4825 (Print)
IS  - 1552-4825 (Linking)
VI  - 131
IP  - 2
DP  - 2004 Dec 1
TI  - Partial trisomy of chromosome 10(q22-q24) due to maternal insertional 
      translocation (15;10).
PG  - 190-3
AB  - Interchromosomal insertional translocations are rare chromosome rearrangements 
      with an incidence of about 1:80,000 live births. We report on the clinical and 
      cytogenetic findings of a newborn baby with partial trisomy 10q22-10q24 due to a 
      maternal insertional translocation 15;10. Partial trisomy of the long arm of 
      chromosome 10 is a distinctive chromosome aberration characterized by 
      prenatal-onset growth retardation and craniofacial, skeletal, and other somatic 
      anomalies. Most cases are unbalanced products from reciprocal chromosome 
      translocations, and insertional translocations are rarely involved. The proband 
      was initially referred because of severe intrauterine growth retardation, and 
      fluorescence in situ hybridization (FISH) using painting probes confirmed the 
      maternal balanced (15;10) insertion.
FAU - Han, J Y
AU  - Han JY
AD  - Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, 
      Korea. jyhan@daunet.donga.ac.kr
FAU - Kim, K H
AU  - Kim KH
FAU - Jun, H J
AU  - Jun HJ
FAU - Je, G H
AU  - Je GH
FAU - Glotzbach, C D
AU  - Glotzbach CD
FAU - Shaffer, L G
AU  - Shaffer LG
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Am J Med Genet A
JT  - American journal of medical genetics. Part A
JID - 101235741
SB  - IM
MH  - Abnormalities, Multiple/genetics
MH  - *Chromosomes, Human, Pair 10
MH  - *Chromosomes, Human, Pair 15
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Infant, Newborn
MH  - Male
MH  - *Translocation, Genetic
MH  - *Trisomy
EDAT- 2004/10/09 09:00
MHDA- 2005/05/06 09:00
CRDT- 2004/10/09 09:00
PHST- 2004/10/09 09:00 [pubmed]
PHST- 2005/05/06 09:00 [medline]
PHST- 2004/10/09 09:00 [entrez]
AID - 10.1002/ajmg.a.30307 [doi]
PST - ppublish
SO  - Am J Med Genet A. 2004 Dec 1;131(2):190-3. doi: 10.1002/ajmg.a.30307.