PMID- 15492794
OWN - NLM
STAT- MEDLINE
DCOM- 20041221
LR  - 20191210
IS  - 1021-335X (Print)
IS  - 1021-335X (Linking)
VI  - 12
IP  - 5
DP  - 2004 Nov
TI  - The effectiveness of artificial neural networks in evaluating treatment plans for 
      patients requiring external beam radiotherapy.
PG  - 1065-70
AB  - This study was designed to determine the ability of a neural network to use data 
      summarized in artificial generated dose volume histograms (DVH) for the rectum to 
      evaluate and compare different patient treatment plans for the treatment of 
      localized prostate cancer. One radiotherapist evaluated 250 artificially 
      generated DVHs representing the distribution of a dose of ration throughout the 
      rectum during external radiotherapy for patients with prostatic adenocarcinoma 
      (PAC). The data were also analyzed using the Lyman NTCP-model for assessing 
      complication probabilities. A neural network consisting of 10 input nodes and one 
      output node was trained to categorize the plans according to the radiotherapist's 
      score. The volume in each isodose was used as input, and the risk for a severe 
      complication was presented as output. The classifications made by the neural 
      network matched those determined by the radiotherapist and the NTCP-model. All 
      three techniques showed a high correlation between each other. Artificially 
      generated dose volume histograms (DVH) for the rectum can be used for training a 
      neural network for scoring rectal DVHs in treatment plans for localized prostate 
      cancer.
FAU - Lennernas, Bo
AU  - Lennernas B
AD  - Department of Oncology, Jubileumskliniken, Sahlgrenska University Hospital, SE 
      413 45 Goteborg, Sweden. bo.lennernas@telia.com
FAU - Sandberg, Dan
AU  - Sandberg D
FAU - Albertsson, Per
AU  - Albertsson P
FAU - Silen, Ake
AU  - Silen A
FAU - Isacsson, Ulf
AU  - Isacsson U
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Greece
TA  - Oncol Rep
JT  - Oncology reports
JID - 9422756
SB  - IM
MH  - Adenocarcinoma/*radiotherapy
MH  - Humans
MH  - Male
MH  - *Neural Networks, Computer
MH  - Prostatic Neoplasms/*radiotherapy
MH  - *Radiotherapy Planning, Computer-Assisted
MH  - *Radiotherapy, Conformal
MH  - Rectum/*anatomy & histology
EDAT- 2004/10/20 09:00
MHDA- 2004/12/22 09:00
CRDT- 2004/10/20 09:00
PHST- 2004/10/20 09:00 [pubmed]
PHST- 2004/12/22 09:00 [medline]
PHST- 2004/10/20 09:00 [entrez]
PST - ppublish
SO  - Oncol Rep. 2004 Nov;12(5):1065-70.