PMID- 15496333
OWN - NLM
STAT- MEDLINE
DCOM- 20050428
LR  - 20061115
IS  - 0731-7085 (Print)
IS  - 0731-7085 (Linking)
VI  - 36
IP  - 2
DP  - 2004 Oct 29
TI  - Solid-phase microextraction-gas chromatography-mass spectrometric analysis of 
      volatile compounds in a compounded Chinese medicinal prescription, 
      Xiao-Cheng-Qi-Tang.
PG  - 381-5
AB  - In this paper, a headspace solid-phase microextraction (HS-SPME) coupled to gas 
      chromatography-mass spectrometry (GC-MS) was applied for the analysis of volatile 
      compounds in a famous compounded Chinese medicinal prescription, 
      Xiao-Cheng-Qi-Tang. Some parameters affecting the extraction efficiency such as 
      stirring, extraction temperature, fiber exposure time and desorption time were 
      optimized. The best results were obtained using a 100 microm PDMS fiber during 
      headspace extraction at 90 degrees C with stirring at 1000 rpm for 20 min. 
      Twenty-seven compounds were identified in Xiao-Cheng-Qi-Tang including some main 
      compounds such as d-limonene and linalool. Inter- and intra-day relative standard 
      deviations (R.S.Ds.) were less than 15.6%, showing that the method had a good 
      reproducibility. The result might provide some foundation for building the 
      convincing theory on the pharmacological activity of this prescription.
FAU - Sha, Yunfei
AU  - Sha Y
AD  - Department of Pharmaceutical Analysis, Fudan University, 138 Yixueyuan Raod, 
      Shanghai 200032, PR China.
FAU - Shen, Shun
AU  - Shen S
FAU - Duan, Gengli
AU  - Duan G
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Pharm Biomed Anal
JT  - Journal of pharmaceutical and biomedical analysis
JID - 8309336
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Indicators and Reagents)
RN  - 0 (Solutions)
RN  - 0 (xiao-cheng-qi-tang)
SB  - IM
MH  - Drugs, Chinese Herbal/*analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Indicators and Reagents
MH  - Reproducibility of Results
MH  - Solutions
MH  - Temperature
EDAT- 2004/10/22 09:00
MHDA- 2005/04/29 09:00
CRDT- 2004/10/22 09:00
PHST- 2004/04/06 00:00 [received]
PHST- 2004/06/09 00:00 [revised]
PHST- 2004/06/11 00:00 [accepted]
PHST- 2004/10/22 09:00 [pubmed]
PHST- 2005/04/29 09:00 [medline]
PHST- 2004/10/22 09:00 [entrez]
AID - S0731708504002638 [pii]
AID - 10.1016/j.jpba.2004.06.009 [doi]
PST - ppublish
SO  - J Pharm Biomed Anal. 2004 Oct 29;36(2):381-5. doi: 10.1016/j.jpba.2004.06.009.