PMID- 15507299
OWN - NLM
STAT- MEDLINE
DCOM- 20041229
LR  - 20181130
IS  - 0165-2427 (Print)
IS  - 0165-2427 (Linking)
VI  - 102
IP  - 3
DP  - 2004 Dec 8
TI  - The immune response to equine arteritis virus: potential lessons for other 
      arteriviruses.
PG  - 107-29
AB  - The members of the family Arteriviridae, genus Arterivirus, include equine 
      arteritis virus (EAV), porcine reproductive and respiratory syndrome virus 
      (PRRSV), lactate dehydrogenase-elevating virus (LDV) of mice, and simian 
      hemorrhagic fever virus (SHFV). PRRSV is the newest member of the family (first 
      isolated in North America and Europe in the early 1990s), whereas the other three 
      viruses were recognized earlier (EAV in 1953, LDV in 1960, and SHFV in 1964). 
      Although arterivirus infections are strictly species-specific, the causative 
      agents share many biological and molecular properties, including their virion 
      morphology, replication strategy, unique properties of their structural proteins, 
      and their ability to establish distinctive persistent infections in their natural 
      hosts. The arteriviruses are each antigenically distinct and cause different 
      disease syndromes in their natural hosts. Similarly, the mechanism(s) responsible 
      for the prolonged and/or persistent infections that characterize infections with 
      each arterivirus in their natural hosts are remarkably different. The objective 
      of this review is to compare and contrast the immune response to EAV with that to 
      the other three arteriviruses, and emphasize the potential relevance of apparent 
      similarities and differences in the neutralization characteristics of each virus.
FAU - Balasuriya, Udeni B R
AU  - Balasuriya UB
AD  - Equine Viral Disease Laboratory, Department of Pathology, Microbiology and 
      Immunology, School of Veterinary Medicine, University of California, Davis, CA 
      95616, USA. ubbalasuriya@ucdavis.edu
FAU - MacLachlan, N James
AU  - MacLachlan NJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
PL  - Netherlands
TA  - Vet Immunol Immunopathol
JT  - Veterinary immunology and immunopathology
JID - 8002006
RN  - 0 (Vaccines, Synthetic)
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - Arterivirus Infections/immunology/*veterinary
MH  - Equartevirus/*immunology
MH  - Genetic Engineering/veterinary
MH  - Horse Diseases/*immunology
MH  - Horses/immunology
MH  - Vaccines, Synthetic/immunology
MH  - Viral Vaccines/immunology
RF  - 171
EDAT- 2004/10/28 09:00
MHDA- 2004/12/30 09:00
CRDT- 2004/10/28 09:00
PHST- 2004/10/28 09:00 [pubmed]
PHST- 2004/12/30 09:00 [medline]
PHST- 2004/10/28 09:00 [entrez]
AID - S0165-2427(04)00233-8 [pii]
AID - 10.1016/j.vetimm.2004.09.003 [doi]
PST - ppublish
SO  - Vet Immunol Immunopathol. 2004 Dec 8;102(3):107-29. doi: 
      10.1016/j.vetimm.2004.09.003.