PMID- 15510582
OWN - NLM
STAT- MEDLINE
DCOM- 20050208
LR  - 20161020
IS  - 1088-5412 (Print)
IS  - 1088-5412 (Linking)
VI  - 25
IP  - 4
DP  - 2004 Jul-Aug
TI  - Salmon caviar-induced anaphylactic shock.
PG  - 233-6
AB  - Foods, particularly shellfish and nuts, are commonly implicated as causes of 
      anaphylaxis. Salmon caviar, to our knowledge, is an exceedingly rare cause of 
      anaphylactic shock. This study describes a patient who experienced anaphylactic 
      shock on her initial ingestion of caviar. Skin testing and inhibition assays 
      using the enzyme-linked immunosorbent assay were performed. On the percutaneous 
      test, the patient had a 7 x 9 mm/15 x 55 mm wheal/ erythema reaction to caviar 
      liquid. Caviar liquid caused 68, 73, and 73% inhibition of immunoglobulin E (IgE) 
      binding at concentrations of 0.01, 0.1, and 1.0 mg/mL in an enzyme-linked 
      immunosorbent assay, respectively. There was no evidence for IgE antibodies that 
      could be demonstrated to bind to the caviar eggs. Despite using both metoprolol 
      and lisinopril, the patient responded promptly to subcutaneous epinephrine. This 
      report indicates that an IgE-mediated response occurred after caviar ingestion. 
      Although she experienced anaphylactic shock, the patient recovered quickly after 
      epinephrine administration despite routine use of a 3-adrenergic blocker and 
      angiotensin-converting enzyme inhibitor.
FAU - Flais, Michael J
AU  - Flais MJ
AD  - Division of Allergy-Immunology, Department of Medicine, Northwestern University 
      Feinberg School of Medicine, Chicago, Illinois 60611, USA.
FAU - Kim, Susan S
AU  - Kim SS
FAU - Harris, Kathleen E
AU  - Harris KE
FAU - Greenberger, Paul A
AU  - Greenberger PA
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Allergy Asthma Proc
JT  - Allergy and asthma proceedings
JID - 9603640
SB  - IM
MH  - Anaphylaxis/*etiology/immunology/therapy
MH  - Animals
MH  - Eggs/*adverse effects
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - *Salmon/immunology
EDAT- 2004/10/30 09:00
MHDA- 2005/02/09 09:00
CRDT- 2004/10/30 09:00
PHST- 2004/10/30 09:00 [pubmed]
PHST- 2005/02/09 09:00 [medline]
PHST- 2004/10/30 09:00 [entrez]
PST - ppublish
SO  - Allergy Asthma Proc. 2004 Jul-Aug;25(4):233-6.