PMID- 15519262 OWN - NLM STAT- MEDLINE DCOM- 20050302 LR - 20071115 IS - 1099-5129 (Print) IS - 1099-5129 (Linking) VI - 6 IP - 6 DP - 2004 Nov TI - Reduction in hospitalization rates following cardiac resynchronisation therapy in cardiac failure: experience from a single centre. PG - 586-9 AB - AIMS: Frequent, lengthy hospital admissions for congestive cardiac failure (CCF) result in excessive health care costs. Cardiac resynchronisation therapy (CRT) is a novel treatment option for patients with CCF and associated cardiac conduction defects. We investigated whether CRT resulted in significant improvements in New York Heart Association (NYHA) symptom class, exercise tolerance, and hospitalization rates in such patients. METHODS: Twenty-seven patients who underwent CRT in a single centre were studied, with NYHA symptom class, exercise tolerance and hospitalization rates noted in the 12 months prior to and following CRT. RESULTS: Following 12 months of CRT, NYHA symptom class improved from 3.3 +/- 0.5 to 2.1 +/- 0.4 (P < 0.05). Exercise tolerance, assessed by 6 min hall walk test increased by 64% from 195 +/- 114 m to 320 +/- 85 m (P = 0.007). Days in hospital for stabilisation of cardiac failure decreased by 98% from 472 to 9 days (P < 0.001). Significant hospitalization cost savings of 201,684 euros were calculated, with an overall saving of 12,420 euros. CONCLUSIONS: These data demonstrate that CRT results in significant improvement in clinical parameters, and considerable reductions in hospital admissions, and costs in patients with CCF. FAU - Dixon, Lana J AU - Dixon LJ AD - Regional Cardiology Centre, Belfast City Hospital, Northern Ireland. l.dixon@qub.ac.uk FAU - Murtagh, J Gerry AU - Murtagh JG FAU - Richardson, S Geoff AU - Richardson SG FAU - Chew, Eng Wooi AU - Chew EW LA - eng PT - Journal Article PL - England TA - Europace JT - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JID - 100883649 SB - IM MH - Aged MH - *Cardiac Pacing, Artificial/economics MH - Female MH - Heart Failure/*therapy MH - Hospitalization/economics/*statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Northern Ireland MH - Pacemaker, Artificial/economics MH - Patient Readmission/economics/statistics & numerical data EDAT- 2004/11/03 09:00 MHDA- 2005/03/03 09:00 CRDT- 2004/11/03 09:00 PHST- 2004/02/12 00:00 [received] PHST- 2004/08/02 00:00 [accepted] PHST- 2004/11/03 09:00 [pubmed] PHST- 2005/03/03 09:00 [medline] PHST- 2004/11/03 09:00 [entrez] AID - S1099-5129(04)00225-9 [pii] AID - 10.1016/j.eupc.2004.08.006 [doi] PST - ppublish SO - Europace. 2004 Nov;6(6):586-9. doi: 10.1016/j.eupc.2004.08.006.