PMID- 15522904
OWN - NLM
STAT- MEDLINE
DCOM- 20050603
LR  - 20061115
IS  - 0931-0509 (Print)
IS  - 0931-0509 (Linking)
VI  - 20
IP  - 1
DP  - 2005 Jan
TI  - Expanding the donor pool to increase renal transplantation.
PG  - 34-41
AB  - INTRODUCTION: The goal of the Eurotransplant renal allocation scheme is to 
      provide every patient on the waiting list with a reasonably balanced opportunity 
      for a donor offer. New initiatives were taken in order to maximize donor usage 
      while maintaining a successful transplant outcome. METHODS: Two Eurotransplant 
      projects were launched in order to accommodate changes in donor and recipient 
      profiles. A re-addressing of the non-heart-beating donor pool was undertaken and 
      an allocation scheme in which organs from donors aged >65 are allocated to 
      recipients aged >65 [the Eurotransplant Senior Programme (ESP)] was introduced. 
      RESULTS: Especially in The Netherlands, an enormous increase in the number of 
      non-heart-beating donor kidneys has been observed, however with a pace-keeping 
      reduction in heart-beating donors. The organization-wide implementation of the 
      ESP has been successful. The 3 year graft survival rates for these age-matched 
      transplants were as good as the human leukocyte antigen (HLA)-matched transplants 
      (64 vs 67%) (P = 0.4). CONCLUSION: Within the framework of sound research, the 
      utmost flexibility and creativity is needed to keep or even increase the number 
      of renal transplants when faced with a quantitatively stagnating but 
      qualitatively deteriorating donor pool. Both the non-heart-beating donor protocol 
      and the ESP have proven to be quite successful in achieving this goal without 
      compromising the outcome for the individual end-stage renal disease patient.
FAU - Cohen, Bernard
AU  - Cohen B
AD  - Eurotransplant International Foundation, Leiden, The Netherlands. 
      bcohen@eurotransplant.nl
FAU - Smits, Jacqueline M
AU  - Smits JM
FAU - Haase, Bernadette
AU  - Haase B
FAU - Persijn, Guido
AU  - Persijn G
FAU - Vanrenterghem, Yves
AU  - Vanrenterghem Y
FAU - Frei, Ulrich
AU  - Frei U
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
DEP - 20041102
PL  - England
TA  - Nephrol Dial Transplant
JT  - Nephrology, dialysis, transplantation : official publication of the European 
      Dialysis and Transplant Association - European Renal Association
JID - 8706402
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Child
MH  - Child, Preschool
MH  - Europe
MH  - Female
MH  - Germany
MH  - Humans
MH  - Incidence
MH  - Kidney Failure, Chronic/diagnosis/*surgery
MH  - Kidney Transplantation/methods/*statistics & numerical data
MH  - Living Donors/statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Netherlands
MH  - Program Development
MH  - Program Evaluation
MH  - Risk Factors
MH  - Tissue Donors/*statistics & numerical data
MH  - Tissue and Organ Procurement/*organization & administration
RF  - 20
EDAT- 2004/11/04 09:00
MHDA- 2005/06/04 09:00
CRDT- 2004/11/04 09:00
PHST- 2004/11/04 09:00 [pubmed]
PHST- 2005/06/04 09:00 [medline]
PHST- 2004/11/04 09:00 [entrez]
AID - gfh506 [pii]
AID - 10.1093/ndt/gfh506 [doi]
PST - ppublish
SO  - Nephrol Dial Transplant. 2005 Jan;20(1):34-41. doi: 10.1093/ndt/gfh506. Epub 2004 
      Nov 2.