PMID- 15526979
OWN - NLM
STAT- MEDLINE
DCOM- 20041209
LR  - 20190516
IS  - 1058-0468 (Print)
IS  - 1573-7330 (Electronic)
IS  - 1058-0468 (Linking)
VI  - 21
IP  - 6
DP  - 2004 Jun
TI  - Spontaneous pregnancies in a Turner syndrome woman with Y-chromosome mosaicism.
PG  - 229-30
AB  - PURPOSE: To present a case involving pregnancies in a Turner woman with 
      Y-chromosome mosaicism. METHOD: A descriptive case report of a single patient. 
      RESULTS: A 39-year-old woman was admitted to the endocrine clinic due to fatigue 
      and premature menopause. She had tried in-vitro fertilization and oocyte donation 
      twice without pregnancies but became spontaneously pregnant at age 36 and 37 and 
      delivered two girls. During the seventh month of the second pregnancy, a 
      dissecting aortic aneurysm, a coarctation, and subsequently a pheochromocytoma 
      were detected and repaired. Hypothyroidism developed. Turner syndrome was 
      diagnosed. Fluorescence in situ hybridization (FISH) analysis of lymphocytes 
      revealed 31% XY cells and 4% XYY cells, while 66% of buccal cells had an XY 
      constitution. Oophorectomy revealed no malignancy. FISH revealed 54% XY cells in 
      the left gonad and 38% XY cells in the right. CONCLUSION: Turner syndrome should 
      be suspected in women with aortic dissection, in general, but especially in those 
      with additional features such as horseshoe kidney, coarctation, and infertility.
FAU - Landin-Wilhelmsen, Kerstin
AU  - Landin-Wilhelmsen K
AD  - Endocrine Division, Sahlgrenska University Hospital, Goteborg, Sweden. 
      kerstin.landin@sahlgrenska.se
FAU - Bryman, Inger
AU  - Bryman I
FAU - Hanson, Charles
AU  - Hanson C
FAU - Hanson, Lars
AU  - Hanson L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - J Assist Reprod Genet
JT  - Journal of assisted reproduction and genetics
JID - 9206495
SB  - IM
MH  - Adult
MH  - Chromosomes, Human, Y/*genetics
MH  - Female
MH  - Humans
MH  - *Mosaicism
MH  - Pregnancy
MH  - Turner Syndrome/*genetics
PMC - PMC3455230
EDAT- 2004/11/06 09:00
MHDA- 2004/12/16 09:00
PMCR- 2005/06/01
CRDT- 2004/11/06 09:00
PHST- 2004/11/06 09:00 [pubmed]
PHST- 2004/12/16 09:00 [medline]
PHST- 2004/11/06 09:00 [entrez]
PHST- 2005/06/01 00:00 [pmc-release]
AID - 490192 [pii]
AID - 10.1023/b:jarg.0000040239.40913.c3 [doi]
PST - ppublish
SO  - J Assist Reprod Genet. 2004 Jun;21(6):229-30. doi: 
      10.1023/b:jarg.0000040239.40913.c3.