PMID- 15539011
OWN - NLM
STAT- MEDLINE
DCOM- 20050307
LR  - 20221207
IS  - 1534-4827 (Print)
IS  - 1534-4827 (Linking)
VI  - 4
IP  - 6
DP  - 2004 Dec
TI  - Diabetic nephropathy in African-American patients.
PG  - 455-61
AB  - Diabetic nephropathy (DN) is the number one cause of end-stage renal disease 
      (ESRD) in the United States and is highly prevalent in African Americans. Since 
      1997, DN has been the number one cause of ESRD in African Americans. In African 
      Americans, almost all DN is due to type 2 diabetes mellitus (T2DM), and 
      nephropathy may affect female more than male patients. African Americans with 
      T2DM are at increased risk for developing and having progression of DN. Glycemic 
      control, development of albuminuria, family history of renal disease, and control 
      of blood pressure are important risk factors for progression of DN. In addition, 
      cigarette smoking, presence of hepatitis C, and use of thiazolinediones has an 
      impact on renal survival in African Americans. Large vessel complications may be 
      less frequent in African Americans with T2DM, when compared with white persons. 
      Yet, cardiovascular disease and other microvascular complications are very 
      common, and both are dependent on control of blood pressure. Achieving the 
      recommended blood pressure of less than 130/80 mm Hg is essential but requires 
      multiple antihypertensive medications, including an inhibitor of the 
      renin-angiotensin system.
FAU - Crook, Errol D
AU  - Crook ED
AD  - University Health Clinic, Wayne State University School of Medicine, 4201 St. 
      Antoine, Suite 2E, Detroit, MI 48201, USA. ecrook@med.wayne.edu
FAU - Patel, Sejal R
AU  - Patel SR
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Diab Rep
JT  - Current diabetes reports
JID - 101093791
SB  - IM
MH  - Adult
MH  - Black or African American/*statistics & numerical data
MH  - Diabetes Mellitus, Type 2/epidemiology
MH  - Diabetic Nephropathies/*epidemiology/mortality
MH  - Female
MH  - Humans
MH  - Male
MH  - Risk Factors
MH  - Smoking
MH  - United States/epidemiology
RF  - 52
EDAT- 2004/11/13 09:00
MHDA- 2005/03/08 09:00
CRDT- 2004/11/13 09:00
PHST- 2004/11/13 09:00 [pubmed]
PHST- 2005/03/08 09:00 [medline]
PHST- 2004/11/13 09:00 [entrez]
AID - 10.1007/s11892-004-0056-y [doi]
PST - ppublish
SO  - Curr Diab Rep. 2004 Dec;4(6):455-61. doi: 10.1007/s11892-004-0056-y.