PMID- 15546706
OWN - NLM
STAT- MEDLINE
DCOM- 20050208
LR  - 20131121
IS  - 0165-1781 (Print)
IS  - 0165-1781 (Linking)
VI  - 132
IP  - 1
DP  - 2004 Nov 15
TI  - Relationship between performance on the Stroop test and N-acetylaspartate in the 
      medial prefrontal cortex in deficit and nondeficit schizophrenia: preliminary 
      results.
PG  - 87-9
AB  - The aim of this research was to investigate the relationship between performance 
      on the Stroop test and N-acetylaspartate/creatine assessed using proton magnetic 
      resonance spectroscopy in the medial prefrontal cortex (MPFC) of schizophrenia 
      patients. The Schedule for the Deficit Syndrome was used to subdivide the 
      schizophrenia patients into deficit (n=5) and nondeficit (n=17) subtypes. 
      Twenty-one control subjects served as a comparison group. A strong correlation 
      between right-sided N-acetylaspartate/creatine levels and Stroop scores was found 
      in the deficit patients but not in the nondeficit patients and the controls. This 
      result suggests a relationship between a dysfunction of the right medial 
      prefrontal cortex and a deficit in selective attention in schizophrenia patients 
      with the deficit syndrome.
FAU - Delamillieure, Pascal
AU  - Delamillieure P
AD  - Groupe d'Imagerie Neurofonctionnelle, UMR 6194 CNRS, Centre Cyceron, Bd H. 
      Becquerel and Centre Esquirol, Centre Hospitalier et Universitaire, Avenue Cote 
      de Nacre, 14000 Caen, France. delamillieure-p@chu-caen.fr
FAU - Constans, Jean-Marc
AU  - Constans JM
FAU - Fernandez, Jesus
AU  - Fernandez J
FAU - Brazo, Perrine
AU  - Brazo P
FAU - Dollfus, Sonia
AU  - Dollfus S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
RN  - 30KYC7MIAI (Aspartic Acid)
RN  - 997-55-7 (N-acetylaspartate)
SB  - IM
MH  - Aspartic Acid/*analogs & derivatives/*metabolism
MH  - Cognition Disorders/diagnosis/*etiology/*physiopathology
MH  - Humans
MH  - *Neuropsychological Tests
MH  - Prefrontal Cortex/*metabolism/*physiopathology
MH  - *Schizophrenia/complications/diagnosis/physiopathology
MH  - Severity of Illness Index
EDAT- 2004/11/18 09:00
MHDA- 2005/02/09 09:00
CRDT- 2004/11/18 09:00
PHST- 2004/03/14 00:00 [received]
PHST- 2004/06/16 00:00 [accepted]
PHST- 2004/11/18 09:00 [pubmed]
PHST- 2005/02/09 09:00 [medline]
PHST- 2004/11/18 09:00 [entrez]
AID - S0925-4927(04)00099-X [pii]
AID - 10.1016/j.pscychresns.2004.06.006 [doi]
PST - ppublish
SO  - Psychiatry Res. 2004 Nov 15;132(1):87-9. doi: 10.1016/j.pscychresns.2004.06.006.