PMID- 1554737
OWN - NLM
STAT- MEDLINE
DCOM- 19920501
LR  - 20190609
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1120
IP  - 1
DP  - 1992 Mar 27
TI  - Koningic acid (heptelidic acid) inhibition of glyceraldehyde-3-phosphate 
      dehydrogenases from various sources.
PG  - 113-6
AB  - Koningic acid is a potent inhibitor of glyceraldehyde-3-phosphate dehydrogenase 
      (GAPDH), which binds to the cysteine residue at the active site. We have 
      determined sensitivity of GAPDHs in comparison with their amino acid sequences. 
      It was found that koningic acid sensitivity of GAPDHs is highly dependent on the 
      sequences of the S-loop domain of the enzyme.
FAU - Kato, M
AU  - Kato M
AD  - Department of Applied Biological Science, Tokyo Noko University, Japan.
FAU - Sakai, K
AU  - Sakai K
FAU - Endo, A
AU  - Endo A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Sesquiterpenes)
RN  - 57710-57-3 (heptelidic acid)
RN  - EC 1.2.1.- (Glyceraldehyde-3-Phosphate Dehydrogenases)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Binding Sites/drug effects
MH  - Chickens
MH  - Erythrocytes/enzymology
MH  - Glyceraldehyde-3-Phosphate Dehydrogenases/*antagonists & inhibitors
MH  - Humans
MH  - Molecular Sequence Data
MH  - Muscles/enzymology
MH  - Sesquiterpenes/pharmacology
MH  - Swine
EDAT- 1992/03/27 00:00
MHDA- 1992/03/27 00:01
CRDT- 1992/03/27 00:00
PHST- 1992/03/27 00:00 [pubmed]
PHST- 1992/03/27 00:01 [medline]
PHST- 1992/03/27 00:00 [entrez]
AID - 0167-4838(92)90431-C [pii]
AID - 10.1016/0167-4838(92)90431-c [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1992 Mar 27;1120(1):113-6. doi: 
      10.1016/0167-4838(92)90431-c.