PMID- 15553816
OWN - NLM
STAT- MEDLINE
DCOM- 20050201
LR  - 20161018
IS  - 1003-5370 (Print)
IS  - 1003-5370 (Linking)
VI  - 24
IP  - 10
DP  - 2004 Oct
TI  - [Study on relationship between TCM Syndrome types (Xin-qi and Xin-yang 
      deficiency) and contents of cytokines (tumor necrosis factor-alpha and 
      interleukins) in patients with congestive heart failure].
PG  - 876-8
AB  - OBJECTIVE: To explore the relationship between TCM Syndromes types, Xin-qi 
      deficiency (XQD) and Xin-yang deficiency (XYD), and contents of cytokines, 
      including tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), IL-1beta 
      and IL-10 in patients with congestive heart failure (CHF). METHODS: Sixty-seven 
      CHF in-patients with Xin-qi deficiency or Xin-yang deficiency syndrome were 
      enrolled, their NYHA (New York Heart Association) cardiac function was assessed, 
      ejection fraction (EF) and E peak/A peak (E/A) ratio were determined by Doppler 
      ultrasonic echocardiograph, and serum TNF-alpha, II-6, IL-1beta and IL-10 were 
      measured by double antibody sandwich ELISA assay. RESULTS: The cardiac function 
      grading in patients of XQD was mostly of I and II grade, while that in patients 
      of XYD was mostly of III and IV grade (by Ridit analysis, P<0.01). The E/A and EF 
      values were higher in patients of XQD than those in patients of XYD (P<0.01). 
      Levels of TNF-alpha, IL-6 and IL-1beta were higher and IL-10 was lower in 
      patients of XYD than those in patients of XQD (P<0.05 or P<0.01) respectively. 
      CONCLUSION: TNF-alpha, IL-6, IL-1beta and IL-10 probably play an important role 
      in the development process of XQD to XYD, and could be taken as the microcosmic 
      indexes for differentiation of the two syndromes.
FAU - Chen, Rui
AU  - Chen R
AD  - Union Hospital, Tongji Medical College, Huazhong University of Science and 
      Technology, Wuhan 430022. chrui1975@sina.com
FAU - Liang, Feng-xia
AU  - Liang FX
FAU - Huang, Yan-xia
AU  - Huang YX
FAU - Li, Bin
AU  - Li B
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Zhong Xi Yi Jie He Za Zhi
JT  - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese 
      journal of integrated traditional and Western medicine
JID - 9211576
RN  - 0 (Interleukin-1)
RN  - 0 (Interleukin-6)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 130068-27-8 (Interleukin-10)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Diagnosis, Differential
MH  - Female
MH  - Heart Failure/*blood/physiopathology
MH  - Humans
MH  - Interleukin-1/blood
MH  - Interleukin-10/blood
MH  - Interleukin-6/*blood
MH  - Male
MH  - *Medicine, Chinese Traditional
MH  - Middle Aged
MH  - Myocardial Contraction
MH  - Stroke Volume/physiology
MH  - Tumor Necrosis Factor-alpha/*metabolism
MH  - Ventricular Dysfunction, Left/physiopathology
MH  - Ventricular Function, Left
MH  - Yang Deficiency/blood
MH  - Yin Deficiency/blood
EDAT- 2004/11/24 09:00
MHDA- 2005/02/03 09:00
CRDT- 2004/11/24 09:00
PHST- 2004/11/24 09:00 [pubmed]
PHST- 2005/02/03 09:00 [medline]
PHST- 2004/11/24 09:00 [entrez]
PST - ppublish
SO  - Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):876-8.