PMID- 15559757
OWN - NLM
STAT- MEDLINE
DCOM- 20050201
LR  - 20191109
IS  - 1041-6102 (Print)
IS  - 1041-6102 (Linking)
VI  - 16
IP  - 3
DP  - 2004 Sep
TI  - Behavioral and Psychological Signs and Symptoms of Dementia (BPSD) in 
      antipsychotic-naive Alzheimer's Disease patients.
PG  - 337-50
AB  - BACKGROUND/OBJECTIVE: There were few studies identifying the natural unfolding of 
      behavioural and psychological symptoms of dementia (BPSD) in the course of 
      Alzheimer's disease (AD) progression in antipsychotic-naive AD patients. This 
      study aims to examine the specific nature of the association between BPSD in AD 
      and the global severity of illness measured by Global Deterioration Scale(GDS) in 
      antipsychotic-naive AD patients in Korea. METHODS: A total of 562 
      antipsychotics-naive AD patients were recruited from four different groups [a 
      geriatric mental hospital (n = 145), a semi-hospitalized dementia institution (n 
      = 120), a dementia clinic (n = 114) and community-dwelling dementia patients (n = 
      183)]. BPSD exhibited by AD patients were measured using the 25-item Korean 
      version of the BEHAVE-AD. RESULTS: Ninety-two percent (n = 517) of AD patients 
      had at least one BPSD, while 56% (n=315) had 4 or more BPSD. Specific kinds of 
      behavioral disturbance peak at the stages of moderate AD (GDS stage 5) or 
      moderately severe AD (GDS stage 6). AD patients left at home without any 
      treatment had higher frequency of BPSD than did other groups seeking treatment, 
      although all of them were antipsychotic-naive. CONCLUSION: BPSD potentially 
      remediable to treatment were highly frequent in Korean AD patients. Health 
      policies to meet the unmet needs of elderly Koreans are urgently needed, 
      especially for AD patients at home without treatment.
FAU - Suh, Guk-Hee
AU  - Suh GH
AD  - Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University 
      Medical Centre, Seoul, Korea. suhgh@chollian.net
FAU - Kim, Seung Kyum
AU  - Kim SK
LA  - eng
PT  - Journal Article
PL  - England
TA  - Int Psychogeriatr
JT  - International psychogeriatrics
JID - 9007918
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Alzheimer Disease/*diagnosis/*drug therapy/*epidemiology
MH  - *Antipsychotic Agents
MH  - Dementia/diagnosis/psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Mental Disorders/diagnosis/*drug therapy/*epidemiology
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - *Patient Acceptance of Health Care
MH  - Prevalence
MH  - Psychomotor Disorders/diagnosis/*drug therapy/*epidemiology
EDAT- 2004/11/24 09:00
MHDA- 2005/02/03 09:00
CRDT- 2004/11/24 09:00
PHST- 2004/11/24 09:00 [pubmed]
PHST- 2005/02/03 09:00 [medline]
PHST- 2004/11/24 09:00 [entrez]
AID - 10.1017/s1041610204000432 [doi]
PST - ppublish
SO  - Int Psychogeriatr. 2004 Sep;16(3):337-50. doi: 10.1017/s1041610204000432.