PMID- 1556501
OWN - NLM
STAT- MEDLINE
DCOM- 19920504
LR  - 20190724
IS  - 0022-2151 (Print)
IS  - 0022-2151 (Linking)
VI  - 106
IP  - 2
DP  - 1992 Feb
TI  - Expression of carbonic anhydrase isoenzymes in the developing endolymphatic sac 
      of the human fetus and the mouse embryo.
PG  - 98-102
AB  - The distribution of carbonic anhydrase isoenzymes (CA) was analyzed in the 
      developing endolymphatic sac (ES) of the mouse embryo and human fetus using 
      immunohistochemical method. The primordial ES epithelium was labelled with CA I 
      and CA II, but was weakly labelled with CA III and CA V. In the thirteenth and 
      fifteenth gestational day (GD) mice, the ES epithelium was positive for CA I and 
      CA II. After seventeenth GD, the ES epithelium was however weakly positive for CA 
      I and CA II. In the 11 and 12 week old human fetus, the ES epithelium was 
      strongly labelled with CA I and CA II. In the 16 week old human fetus, the ES 
      epithelium was however weakly positive for CA I and CA II. These results suggest 
      that the fetal ES has an activity of CA and plays a role in the otoconial 
      formation especially in the early stage during evolution.
FAU - Yamashita, H
AU  - Yamashita H
AD  - Department of Otolaryngology, Karolinska Hospital, Karolinska Institute, 
      Stockholm, Sweden.
FAU - Bagger-Sjoback, D
AU  - Bagger-Sjoback D
FAU - Sekitani, T
AU  - Sekitani T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Laryngol Otol
JT  - The Journal of laryngology and otology
JID - 8706896
RN  - 0 (Isoenzymes)
RN  - EC 4.2.1.1 (Carbonic Anhydrases)
SB  - IM
MH  - Animals
MH  - Carbonic Anhydrases/*metabolism
MH  - Embryonic and Fetal Development/*physiology
MH  - Endolymphatic Sac/*enzymology
MH  - Gestational Age
MH  - Humans
MH  - Immunohistochemistry
MH  - Isoenzymes/*metabolism
MH  - Mice
MH  - Mice, Inbred CBA
MH  - Microscopy, Fluorescence
EDAT- 1992/02/01 00:00
MHDA- 1992/02/01 00:01
CRDT- 1992/02/01 00:00
PHST- 1992/02/01 00:00 [pubmed]
PHST- 1992/02/01 00:01 [medline]
PHST- 1992/02/01 00:00 [entrez]
AID - 10.1017/s0022215100118808 [doi]
PST - ppublish
SO  - J Laryngol Otol. 1992 Feb;106(2):98-102. doi: 10.1017/s0022215100118808.