PMID- 15575267
OWN - NLM
STAT- MEDLINE
DCOM- 20050307
LR  - 20190714
IS  - 0013-936X (Print)
IS  - 0013-936X (Linking)
VI  - 38
IP  - 21
DP  - 2004 Nov 1
TI  - Analysis of perfluorinated acids at parts-per-quadrillion levels in seawater 
      using liquid chromatography-tandem mass spectrometry.
PG  - 5522-8
AB  - Perfluorinated acids (PFAs) and their salts have emerged as an important class of 
      global environmental contaminants. Determination of sub-parts-per-trillion or 
      parts-per-quadrillion concentrations of perfluorinated acids in aqueous media has 
      been impeded by relatively high background levels arising from procedural or 
      instrumental blanks. To understand the role of the oceans in the transport and 
      fate of perfluorinated acids, methods to determine ultratrace levels of these 
      compounds in seawater are needed. In this study, sources of procedural and 
      instrumental blank contamination by perfluorinated acids have been identified and 
      eliminated, to reduce background levels in blanks and thereby improve limits of 
      quantitation. The method developed in this study is capable of detecting 
      perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS), 
      perfluorobutanesulfonate (PFBS), perfluorooctanoate (PFOA), perfluorononanoate 
      (PFNA), and perfluorooctanesulfonamide (PFOSA) at low pg/L levels in oceanic 
      waters. PFOA is the major perfluorinated compound detected in oceanic waters, 
      followed by PFOS. Further studies are being conducted to elucidate the 
      distribution and fate of perfluorinated acids in oceans.
FAU - Yamashita, Nobuyoshi
AU  - Yamashita N
AD  - National Institute of Advanced Industrial Science and Technology, 16-1 Onogawa, 
      Tsukuba, Ibaraki 305-8569, Japan.
FAU - Kannan, Kurunthachalam
AU  - Kannan K
FAU - Taniyasu, Sachi
AU  - Taniyasu S
FAU - Horii, Yuichi
AU  - Horii Y
FAU - Okazawa, Tsuyoshi
AU  - Okazawa T
FAU - Petrick, Gert
AU  - Petrick G
FAU - Gamo, Toshitaka
AU  - Gamo T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Environ Sci Technol
JT  - Environmental science & technology
JID - 0213155
RN  - 0 (Alkanesulfonic Acids)
RN  - 0 (Fluorocarbons)
RN  - 9H2MAI21CL (perfluorooctane sulfonic acid)
SB  - IM
MH  - Alkanesulfonic Acids/analysis
MH  - Chromatography, Liquid/*methods
MH  - Environmental Exposure
MH  - Environmental Monitoring/*methods
MH  - Fluorocarbons/*analysis
MH  - Mass Spectrometry/*methods
MH  - Seawater/*analysis/chemistry
EDAT- 2004/12/04 09:00
MHDA- 2005/03/08 09:00
CRDT- 2004/12/04 09:00
PHST- 2004/12/04 09:00 [pubmed]
PHST- 2005/03/08 09:00 [medline]
PHST- 2004/12/04 09:00 [entrez]
AID - 10.1021/es0492541 [doi]
PST - ppublish
SO  - Environ Sci Technol. 2004 Nov 1;38(21):5522-8. doi: 10.1021/es0492541.