PMID- 15578375 OWN - NLM STAT- MEDLINE DCOM- 20051108 LR - 20041203 IS - 1537-6591 (Electronic) IS - 1058-4838 (Linking) VI - 39 IP - 11 DP - 2004 Dec 1 TI - Determinants of immune reconstitution inflammatory syndrome in HIV type 1-infected patients with tuberculosis after initiation of antiretroviral therapy. PG - 1709-12 AB - Immune reconstitution inflammatory syndrome (IRIS) occurred in 16 of 37 antiretroviral-naive patients who were treated subsequently for tuberculosis and human immunodeficiency virus (HIV) type 1 infection. IRIS was related to increases in the CD4 cell percentage and in the ratio of CD4 cells to CD8 cells after 1 month of antiretroviral therapy and to dissemination of tuberculosis. These results have implications for the diagnosis of IRIS and the understanding of its pathogenesis. FAU - Breton, Guillaume AU - Breton G AD - Department of Infectious and Tropical Diseases, INSERM E0357, Bichat-Claude Bernard Hospital, Assistance Publique-Hopitaux de Paris, Paris, France. guillaume.breton@bch.ap-hop-paris.fr FAU - Duval, Xavier AU - Duval X FAU - Estellat, Candice AU - Estellat C FAU - Poaletti, Xavier AU - Poaletti X FAU - Bonnet, Daniel AU - Bonnet D FAU - Mvondo Mvondo, David AU - Mvondo Mvondo D FAU - Longuet, Pascale AU - Longuet P FAU - Leport, Catherine AU - Leport C FAU - Vilde, Jean-Louis AU - Vilde JL LA - eng PT - Journal Article DEP - 20041109 PL - United States TA - Clin Infect Dis JT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JID - 9203213 RN - 0 (Anti-Retroviral Agents) SB - IM MH - Adult MH - Anti-Retroviral Agents/*therapeutic use MH - Female MH - HIV Infections/complications/*drug therapy/*immunology MH - *HIV-1 MH - Humans MH - Inflammation/etiology MH - Male MH - Middle Aged MH - Retrospective Studies MH - Syndrome MH - Tuberculosis/complications/*immunology EDAT- 2004/12/04 09:00 MHDA- 2005/11/09 09:00 CRDT- 2004/12/04 09:00 PHST- 2004/04/21 00:00 [received] PHST- 2004/07/29 00:00 [accepted] PHST- 2004/12/04 09:00 [pubmed] PHST- 2005/11/09 09:00 [medline] PHST- 2004/12/04 09:00 [entrez] AID - CID33845 [pii] AID - 10.1086/425742 [doi] PST - ppublish SO - Clin Infect Dis. 2004 Dec 1;39(11):1709-12. doi: 10.1086/425742. Epub 2004 Nov 9.