PMID- 15580918 OWN - NLM STAT- MEDLINE DCOM- 20041229 LR - 20190713 IS - 0032-5481 (Print) IS - 0032-5481 (Linking) VI - 116 IP - 5 DP - 2004 Nov TI - Treatment update on spondyloarthropathy. From NSAIDs and DMARDs to anti-TNF-alpha agents. PG - 31-6, 39-40 AB - Traditionally, nonsteroidal anti-inflammatory drugs (NSAIDs) and disease-modifying antirheumatic agents (DMARDs) have been used to control the symptoms of spondyloarthropathy. With the advent of anti-tumor necrosis factor alpha (anti-TNF-alpha) agents, however, it is now possible to slow disease progression, improve overall function, and provide symptomatic relief of arthritis, skin lesions, and bowel inflammation associated with these disorders. Here, Drs Anandarajah and Ritchlin explore the effectiveness of conventional therapies as well as biologic agents that are currently available or under development. FAU - Anandarajah, Allen P AU - Anandarajah AP AD - Department of Allergy, Immunology and Rheumatology, University of Rochester School of Medicine and Dentistry, New York 14642, USA. FAU - Ritchlin, Christopher T AU - Ritchlin CT LA - eng PT - Journal Article PT - Review PL - England TA - Postgrad Med JT - Postgraduate medicine JID - 0401147 RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 0 (Antirheumatic Agents) RN - 0 (Tumor Necrosis Factor-alpha) SB - IM CIN - Postgrad Med. 2004 Nov;116(5):41-2, 48-50. PMID: 15580919 MH - Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use MH - Antirheumatic Agents/*therapeutic use MH - Humans MH - Spondylarthropathies/*drug therapy MH - Tumor Necrosis Factor-alpha/*therapeutic use RF - 20 EDAT- 2004/12/08 09:00 MHDA- 2004/12/30 09:00 CRDT- 2004/12/08 09:00 PHST- 2004/12/08 09:00 [pubmed] PHST- 2004/12/30 09:00 [medline] PHST- 2004/12/08 09:00 [entrez] AID - 10.3810/pgm.2004.11.1609 [doi] PST - ppublish SO - Postgrad Med. 2004 Nov;116(5):31-6, 39-40. doi: 10.3810/pgm.2004.11.1609.