PMID- 15609775
OWN - NLM
STAT- MEDLINE
DCOM- 20050505
LR  - 20181201
IS  - 1606-0997 (Print)
IS  - 1606-0997 (Linking)
VI  - 22
IP  - 3
DP  - 2004 Sep
TI  - Multidisciplinary studies of disease burden in the Diseases of the Most 
      Impoverished Programme.
PG  - 232-9
AB  - With limited healthcare resources, rational prioritization of healthcare 
      interventions requires knowledge and analysis of disease burden. In the absence 
      of actual disease-burden data from less-developed countries, various types of 
      morbidity and mortality estimates have been made. Besides having questionable 
      reliability, these estimates do not capture the full burden of a disease since 
      they provide only the number of cases and deaths. The modelling methods that 
      include disability are more comprehensive but are difficult to understand, and 
      their reliability is affected by baseline approximations. To provide 
      policy-makers with information needed for rational decision-making, the Diseases 
      of the Most Impoverished (DOMI) Programme of the International Vaccine Institute 
      has used a multidisciplinary approach to describe the burden of disease due to 
      typhoid fever, shigellosis, and cholera. Recognizing the relative advantages and 
      disadvantages of various methodologies, the programme employs passive 
      clinic-based surveillance in defined communities to provide prospective data. The 
      prospective data are complemented with retrospectively-collected information from 
      existing sources, frequently less accurate and complete but readily available for 
      the whole population over extended periods. To create a more complete picture, 
      economic and qualitative studies specific to each disease are incorporated in 
      these prospective studies. The goal is to achieve a more complete and realistic 
      picture by combining the results of these various methodologies, acknowledging 
      the strengths and limitations of each. These projects also build in-country 
      capacity in terms of treatment, diagnosis, epidemiology, and data management.
FAU - Deen, Jacqueline L
AU  - Deen JL
AD  - International Vaccine Institute, Seoul 151-600, Republic of Korea. jdeen@ivi.int
FAU - von Seidlein, Lorenz
AU  - von Seidlein L
FAU - Clemens, John D
AU  - Clemens JD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Bangladesh
TA  - J Health Popul Nutr
JT  - Journal of health, population, and nutrition
JID - 100959228
SB  - IM
MH  - Cholera/mortality/prevention & control
MH  - *Cost of Illness
MH  - *Developing Countries
MH  - Dysentery, Bacillary/mortality/prevention & control
MH  - *Health Surveys
MH  - Humans
MH  - Immunization Programs/*organization & administration
MH  - *Poverty
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Typhoid Fever/mortality/prevention & control
MH  - *Vaccination/methods/statistics & numerical data
EDAT- 2004/12/22 09:00
MHDA- 2005/05/06 09:00
CRDT- 2004/12/22 09:00
PHST- 2004/12/22 09:00 [pubmed]
PHST- 2005/05/06 09:00 [medline]
PHST- 2004/12/22 09:00 [entrez]
PST - ppublish
SO  - J Health Popul Nutr. 2004 Sep;22(3):232-9.