PMID- 15623710
OWN - NLM
STAT- MEDLINE
DCOM- 20050815
LR  - 20190514
IS  - 1526-632X (Electronic)
IS  - 0028-3878 (Linking)
VI  - 63
IP  - 12
DP  - 2004 Dec 28
TI  - Associations with autoimmune disorders and HLA class I and II antigens in 
      inclusion body myositis.
PG  - 2396-8
AB  - Whether autoimmune mechanisms play a role in the pathogenesis of inclusion body 
      myositis (IBM) is unknown. Human leukocyte antigen (HLA) analysis in 52 patients, 
      including 17 with autoimmune disorders (AIDs), showed that patients were more 
      likely to have antigens from the autoimmune-prone HLA-B8-DR3 ancestral haplotype 
      than healthy control subjects, irrespective of the presence of AIDs. Patients 
      lacked the apparently protective HLA-DR53 antigen. The results provide further 
      support for an autoimmune basis in IBM.
FAU - Badrising, U A
AU  - Badrising UA
AD  - Department of Neurology, K5Q, Leiden University Medical Center, PO Box 9600, 2300 
      RC Leiden, The Netherlands. ubadrising@lumc.nl
FAU - Schreuder, G M Th
AU  - Schreuder GM
FAU - Giphart, M J
AU  - Giphart MJ
FAU - Geleijns, K
AU  - Geleijns K
FAU - Verschuuren, J J G M
AU  - Verschuuren JJ
FAU - Wintzen, A R
AU  - Wintzen AR
FAU - Maat-Schieman, M L C
AU  - Maat-Schieman ML
FAU - van Doorn, P
AU  - van Doorn P
FAU - van Engelen, B G M
AU  - van Engelen BG
FAU - Faber, C G
AU  - Faber CG
FAU - Hoogendijk, J E
AU  - Hoogendijk JE
FAU - de Jager, A E
AU  - de Jager AE
FAU - Koehler, P J
AU  - Koehler PJ
FAU - de Visser, M
AU  - de Visser M
FAU - van Duinen, S G
AU  - van Duinen SG
CN  - Dutch IBM Study Group
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Neurology
JT  - Neurology
JID - 0401060
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-D Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DR53)
RN  - 0 (HLA-DRB4 Chains)
SB  - IM
MH  - Age of Onset
MH  - Aged
MH  - Aged, 80 and over
MH  - Autoimmune Diseases/*epidemiology/genetics/immunology
MH  - Comorbidity
MH  - Female
MH  - Gene Frequency
MH  - *Genes, MHC Class I
MH  - *Genes, MHC Class II
MH  - Genetic Predisposition to Disease
MH  - HLA Antigens/*analysis/genetics/immunology
MH  - HLA-D Antigens/*analysis/genetics/immunology
MH  - HLA-DR Antigens/analysis/genetics/immunology
MH  - HLA-DRB4 Chains
MH  - Haplotypes/genetics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myositis, Inclusion Body/*epidemiology/genetics/immunology
MH  - Netherlands/epidemiology
MH  - Prevalence
EDAT- 2004/12/30 09:00
MHDA- 2005/08/16 09:00
CRDT- 2004/12/30 09:00
PHST- 2004/12/30 09:00 [pubmed]
PHST- 2005/08/16 09:00 [medline]
PHST- 2004/12/30 09:00 [entrez]
AID - 63/12/2396 [pii]
AID - 10.1212/01.wnl.0000148588.15052.4c [doi]
PST - ppublish
SO  - Neurology. 2004 Dec 28;63(12):2396-8. doi: 10.1212/01.wnl.0000148588.15052.4c.