PMID- 15624672
OWN - NLM
STAT- MEDLINE
DCOM- 20050217
LR  - 20191109
IS  - 1529-1839 (Print)
IS  - 1558-1527 (Linking)
VI  - 75
IP  - 12
DP  - 2004 Dec
TI  - Polypoidal choroidal vasculopathy.
PG  - 756-70
AB  - BACKGROUND: Polypoidal choroidal vasculopathy (PCV) is a unique form of occult 
      choroidal neovascular membrane. The clinical presentation and angiographic 
      findings distinguish idiopathic PCV from other known neovascular and choroidal 
      degenerative disorders. The characteristic morphology of PCV includes the 
      presence of a branching network of inner choroidal vessels with terminal 
      aneurysmal dilations. Other key findings include subtle nodular protrusions, 
      which may precede multiple serosanguineous retinal pigment epithelial 
      detachments. If Bruch's membrane is compromised, there is an additional risk of 
      exudative retinopathy or vitreal hemorrhage. CASE REPORTS: Three patients with 
      polypoidal choroidal vasculopathy are described with visual impairment secondary 
      to irregular choroidal vascular lesions producing recurrent subretinal 
      hemorrhages and exudative retinopathy. CONCLUSIONS: The characteristic 
      presentation and clinical course of polypoidal choroidal vasculopathy distinguish 
      it from the typical presentation of age-related macular degeneration and other 
      causes of hemorrhagic and exudative retinopathy. Imaging techniques such as 
      fluorescein angiography, indocyanine green angiography, and optical coherence 
      tomography may assist in the accurate diagnosis of PCV, so that appropriate 
      treatment and management can be provided. In patients who manifest exudative, 
      hemorrhagic retinopathy, with no signs of active inflammation or an anatomic 
      predisposition to choroidal neovascularization, PCV should be considered.
FAU - McCleary, Christa D
AU  - McCleary CD
AD  - Bascom Palmer Eye Institute, Miami, Florida, USA. cdmccleary@hotmail.com
FAU - Guier, Christian P
AU  - Guier CP
FAU - Dunbar, Mark T
AU  - Dunbar MT
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Optometry
JT  - Optometry (St. Louis, Mo.)
JID - 100912421
RN  - 0 (Coloring Agents)
RN  - IX6J1063HV (Indocyanine Green)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Choroid/*blood supply/pathology
MH  - Choroid Diseases/*diagnosis
MH  - Coloring Agents
MH  - Female
MH  - Fluorescein Angiography
MH  - Fundus Oculi
MH  - Humans
MH  - Indocyanine Green
MH  - Male
MH  - Middle Aged
EDAT- 2004/12/31 09:00
MHDA- 2005/02/18 09:00
CRDT- 2004/12/31 09:00
PHST- 2004/12/31 09:00 [pubmed]
PHST- 2005/02/18 09:00 [medline]
PHST- 2004/12/31 09:00 [entrez]
AID - 10.1016/s1529-1839(04)70235-3 [doi]
PST - ppublish
SO  - Optometry. 2004 Dec;75(12):756-70. doi: 10.1016/s1529-1839(04)70235-3.