PMID- 15630730
OWN - NLM
STAT- MEDLINE
DCOM- 20050414
LR  - 20061115
IS  - 0315-162X (Print)
IS  - 0315-162X (Linking)
VI  - 32
IP  - 1
DP  - 2005 Jan
TI  - Establishment of the minimum clinically important difference for the bath 
      ankylosing spondylitis indices: a prospective study.
PG  - 80-5
AB  - OBJECTIVE: The minimum clinically important difference (MCID) is the minimum 
      level of change of an outcome measure that is considered to be clinically 
      relevant. This prospective study was conducted to establish the minimum level of 
      change in the Bath Ankylosing Spondylitis (BAS) indices that is meaningful for 
      both the patient and the clinician. METHODS: The BAS questionnaires [i.e., Bath 
      Ankylosing Spondylitis Functional Index (BASFI); Bath Ankylosing Spondylitis 
      Disease Activity Index (BASDAI); and Bath Ankylosing Spondylitis patient Global 
      score (BAS-G)] were administered to 125 patients with ankylosing spondylitis (AS) 
      at baseline and at the end of a 2-week intensive physiotherapy program. Together 
      with the final assessment, a global validated rating scale was used to examine 
      each domain. Receiver operating characteristic (ROC) curves were plotted to 
      determine the BAS change score that most accurately classified patients with 
      respect to a clinically meaningful change. This analysis was repeated to 
      investigate whether the estimate of change was dependent upon the patients' 
      baseline scores. RESULTS: According to analyses of ROC curves, the MCID are 7 mm 
      or 17.5% for BASFI: sensitivity = 0.60/specificity = 0.85; 10 mm or 22.5% for 
      BASDAI: sensitivity = 0.65/specificity = 0.82; and 15 mm or 27.5% for BAS-G: 
      sensitivity = 0.61/specificity = 0.74. MCID values were independent of the 
      patients' baseline scores (p = 0.09 to 0.72) by regression analysis. CONCLUSION: 
      This prospective study gives MCID values for BASFI, BASDAI, and BAS-G that allow 
      translation from the BAS indices to readily understood values for both patients 
      and clinicians.
FAU - Pavy, Stephan
AU  - Pavy S
AD  - Hopital Cochin, Paris, France. stephan.pavy@cch.ap.hop-paris.fr
FAU - Brophy, Sinead
AU  - Brophy S
FAU - Calin, Andrei
AU  - Calin A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - J Rheumatol
JT  - The Journal of rheumatology
JID - 7501984
SB  - IM
CIN - J Rheumatol. 2005 Jan;32(1):1-2. PMID: 15630716
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Male
MH  - Patient Satisfaction
MH  - Prospective Studies
MH  - ROC Curve
MH  - Rheumatology/*methods
MH  - *Severity of Illness Index
MH  - Spondylitis, Ankylosing/*physiopathology/*therapy
MH  - Treatment Outcome
EDAT- 2005/01/05 09:00
MHDA- 2005/04/15 09:00
CRDT- 2005/01/05 09:00
PHST- 2005/01/05 09:00 [pubmed]
PHST- 2005/04/15 09:00 [medline]
PHST- 2005/01/05 09:00 [entrez]
AID - 0315162X-32-80 [pii]
PST - ppublish
SO  - J Rheumatol. 2005 Jan;32(1):80-5.