PMID- 15630746
OWN - NLM
STAT- MEDLINE
DCOM- 20050414
LR  - 20151119
IS  - 0315-162X (Print)
IS  - 0315-162X (Linking)
VI  - 32
IP  - 1
DP  - 2005 Jan
TI  - Successful treatment of long-standing neuro-Behcet's disease with infliximab.
PG  - 181-3
AB  - Behcet's disease is a chronic relapsing form of vasculitis affecting multiple 
      organs. Central nervous system involvement is a common presentation. Tumor 
      necrosis factor-alpha (TNF-alpha) is considered to play a major role in the 
      disease pathogenesis. We describe a patient with a long history of neuro-Behcet's 
      disease who showed a remarkable response to infliximab therapy. Given the 
      variable and limited success of other interventions, the use of anti-TNF-alpha 
      therapy seems to be effective for patients with refractory disease.
FAU - Sarwar, Haroon
AU  - Sarwar H
AD  - Section of Rheumatology, Department of Medicine, Louisiana State University 
      Health Sciences Center, New Orleans, Louisiana 70112, USA.
FAU - McGrath, Hugh Jr
AU  - McGrath H Jr
FAU - Espinoza, Luis R
AU  - Espinoza LR
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - J Rheumatol
JT  - The Journal of rheumatology
JID - 7501984
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - B72HH48FLU (Infliximab)
SB  - IM
MH  - Adult
MH  - Antibodies, Monoclonal/*therapeutic use
MH  - Behcet Syndrome/complications/immunology/*therapy
MH  - Central Nervous System Diseases/complications/immunology/*therapy
MH  - Humans
MH  - Infliximab
MH  - Male
MH  - Remission Induction
MH  - Tumor Necrosis Factor-alpha/*antagonists & inhibitors/immunology
EDAT- 2005/01/05 09:00
MHDA- 2005/04/15 09:00
CRDT- 2005/01/05 09:00
PHST- 2005/01/05 09:00 [pubmed]
PHST- 2005/04/15 09:00 [medline]
PHST- 2005/01/05 09:00 [entrez]
AID - 0315162X-32-181 [pii]
PST - ppublish
SO  - J Rheumatol. 2005 Jan;32(1):181-3.