PMID- 15637417
OWN - NLM
STAT- MEDLINE
DCOM- 20050715
LR  - 20050406
IS  - 0301-1569 (Print)
IS  - 0301-1569 (Linking)
VI  - 67
IP  - 1
DP  - 2005
TI  - Blink reflex R2 recovery curves in patients with facial palsy within ten days 
      after onset.
PG  - 16-22
AB  - The purpose of this study was to investigate the acute changes in blink reflex 
      responses in patients with facial palsy. We used the blink reflex R2 recovery 
      curves as an index of the excitability of the blink reflex neural circuit and 
      evaluated the excitability of the blink reflex within 10 days after onset. Twelve 
      patients with peripheral facial palsy were selected on condition that the degree 
      of facial palsy was so mild that R2 responses of the blink reflex were measurable 
      on the affected side, and they were compared with 12 healthy volunteers. 
      Conditioning and test electrical stimuli were delivered on the affected side of 
      the supraorbital nerve. Ipsilateral R2 response (iR2) of the blink reflex in 
      patients was significantly enhanced at interstimulus intervals (ISIs) between 
      conditioning and test stimuli from 100 to 1,000 ms, in comparison with the 
      control subjects. These findings suggested hyperexcitability of the blink reflex 
      neural circuit in patients with facial palsy. In addition to iR2, contralateral 
      R2 response (cR2) in the patients was also significantly increased at ISIs of 
      100-1,000 ms to the same extent as the enhancement of iR2. All these findings 
      suggested that the hyperexcitable changes developed in a common pathway of iR2 
      and cR2, but not in the ipsilateral facial motor neurons. It is suggested that 
      the hyperexcitability of the neural circuit of the blink reflex during an acute 
      period of facial palsy is an adaptive response to compensate for impaired facial 
      motor function.
CI  - Copyright (c) 2005 S. Karger AG, Basel.
FAU - Toda, Naoki
AU  - Toda N
AD  - Department of Otolaryngology, Kochi National Hospital, Kochi, Japan. 
      mutimaro@d2.dion.nc.jp
FAU - Nakamura, Katsuhiko
AU  - Nakamura K
FAU - Takeda, Noriaki
AU  - Takeda N
LA  - eng
PT  - Journal Article
DEP - 20050104
PL  - Switzerland
TA  - ORL J Otorhinolaryngol Relat Spec
JT  - ORL; journal for oto-rhino-laryngology and its related specialties
JID - 0334721
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blinking/*physiology
MH  - Electromyography
MH  - Facial Paralysis/diagnosis/*physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Recovery of Function
MH  - Reflex/*physiology
EDAT- 2005/01/08 09:00
MHDA- 2005/07/16 09:00
CRDT- 2005/01/08 09:00
PHST- 2003/11/19 00:00 [received]
PHST- 2004/09/09 00:00 [accepted]
PHST- 2005/01/08 09:00 [pubmed]
PHST- 2005/07/16 09:00 [medline]
PHST- 2005/01/08 09:00 [entrez]
AID - 83009 [pii]
AID - 10.1159/000083009 [doi]
PST - ppublish
SO  - ORL J Otorhinolaryngol Relat Spec. 2005;67(1):16-22. doi: 10.1159/000083009. Epub 
      2005 Jan 4.