PMID- 15640107
OWN - NLM
STAT- MEDLINE
DCOM- 20081007
LR  - 20161020
IS  - 0253-9772 (Print)
IS  - 0253-9772 (Linking)
VI  - 26
IP  - 6
DP  - 2004 Nov
TI  - [Tumor necrosis factor-alpha gene polymorphisms and risk of coronary heart 
      disease].
PG  - 807-10
AB  - Tumor necrosis factor-alpha(TNF-alpha) is a cytokine that has multiple functions. 
      It could be involved in cardiovascular pathophysiology. Given this possibility, 
      we measured serum TNF-alpha level by ELISA and use PCR-RFLP methods to examine 
      the distribution of TNF-alpha locus gene polymorphism at -857 and -863 sites in 
      coronary heart disease(CHD) patients and matched controls. We found the serum 
      level of TNF-alpha of CHD is higher than that of controls(P<0.05),-863 genotype 
      and allele have significant difference between two groups(P<0.05),and there are 
      no difference in two groups at -857 site.
FAU - Xiang, Ping-Xia
AU  - Xiang PX
AD  - Department of Medical Laboratory Science, RenMin Hospital of Wuhan University, 
      Wuhan 430060,China. estheresther@sina.com
FAU - Li, Yan
AU  - Li Y
FAU - Zhang, Ping-An
AU  - Zhang PA
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Yi Chuan
JT  - Yi chuan = Hereditas
JID - 9436478
RN  - 0 (Tumor Necrosis Factor-alpha)
SB  - IM
MH  - Aged
MH  - Alleles
MH  - Coronary Disease/blood/*genetics
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Gene Frequency
MH  - Genetic Predisposition to Disease
MH  - Genotype
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Polymerase Chain Reaction
MH  - *Polymorphism, Genetic
MH  - Polymorphism, Restriction Fragment Length
MH  - Tumor Necrosis Factor-alpha/blood/*genetics
EDAT- 2005/01/11 09:00
MHDA- 2008/10/08 09:00
CRDT- 2005/01/11 09:00
PHST- 2005/01/11 09:00 [pubmed]
PHST- 2008/10/08 09:00 [medline]
PHST- 2005/01/11 09:00 [entrez]
AID - 0253-9772(2004)06-0807-04 [pii]
PST - ppublish
SO  - Yi Chuan. 2004 Nov;26(6):807-10.