PMID- 15654102
OWN - NLM
STAT- MEDLINE
DCOM- 20050829
LR  - 20181224
IS  - 0016-6731 (Print)
IS  - 0016-6731 (Linking)
VI  - 169
IP  - 3
DP  - 2005 Mar
TI  - Variogram analysis of the spatial genetic structure of continuous populations 
      using multilocus microsatellite data.
PG  - 1739-52
AB  - A geostatistical perspective on spatial genetic structure may explain 
      methodological issues of quantifying spatial genetic structure and suggest new 
      approaches to addressing them. We use a variogram approach to (i) derive a 
      spatial partitioning of molecular variance, gene diversity, and genotypic 
      diversity for microsatellite data under the infinite allele model (IAM) and the 
      stepwise mutation model (SMM), (ii) develop a weighting of sampling units to 
      reflect ploidy levels or multiple sampling of genets, and (iii) show how 
      variograms summarize the spatial genetic structure within a population under 
      isolation-by-distance. The methods are illustrated with data from a population of 
      the epiphytic lichen Lobaria pulmonaria, using six microsatellite markers. 
      Variogram-based analysis not only avoids bias due to the underestimation of 
      population variance in the presence of spatial autocorrelation, but also provides 
      estimates of population genetic diversity and the degree and extent of spatial 
      genetic structure accounting for autocorrelation.
FAU - Wagner, Helene H
AU  - Wagner HH
AD  - WSL Swiss Federal Research Institute, Birmensdorf, Switzerland. 
      helene.wagner@wsl.ch
FAU - Holderegger, Rolf
AU  - Holderegger R
FAU - Werth, Silke
AU  - Werth S
FAU - Gugerli, Felix
AU  - Gugerli F
FAU - Hoebee, Susan E
AU  - Hoebee SE
FAU - Scheidegger, Christoph
AU  - Scheidegger C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050116
PL  - United States
TA  - Genetics
JT  - Genetics
JID - 0374636
SB  - IM
MH  - Analysis of Variance
MH  - *Chromosome Mapping
MH  - Genetic Variation
MH  - *Genetics, Population
MH  - Genotype
MH  - Microsatellite Repeats/*genetics
MH  - Models, Genetic
MH  - Models, Statistical
MH  - Pulmonaria/genetics
PMC - PMC1449570
EDAT- 2005/01/18 09:00
MHDA- 2005/08/30 09:00
PMCR- 2005/06/01
CRDT- 2005/01/18 09:00
PHST- 2005/01/18 09:00 [pubmed]
PHST- 2005/08/30 09:00 [medline]
PHST- 2005/01/18 09:00 [entrez]
PHST- 2005/06/01 00:00 [pmc-release]
AID - genetics.104.036038 [pii]
AID - 6038 [pii]
AID - 10.1534/genetics.104.036038 [doi]
PST - ppublish
SO  - Genetics. 2005 Mar;169(3):1739-52. doi: 10.1534/genetics.104.036038. Epub 2005 
      Jan 16.