PMID- 1565448
OWN - NLM
STAT- MEDLINE
DCOM- 19920518
LR  - 20190726
IS  - 0161-6420 (Print)
IS  - 0161-6420 (Linking)
VI  - 99
IP  - 3
DP  - 1992 Mar
TI  - Correlation of serum immunoglobulin E elevations with clinical stages of 
      dysthyroid orbitopathy.
PG  - 361-5
AB  - Total immunoglobulin E (IgE) was measured by an enzyme-linked immunoassay in 
      serum samples from patients with dysthyroid orbitopathy and from a group of 
      healthy volunteers. All the serum donors had no symptoms of allergy or infection 
      and were not given any immunoregulative treatments for at least 6 months before 
      the sampling. One hundred thirty-seven dysthyroid orbitopathy patients were rated 
      clinically as belonging to one of the following groups: (1) stable dysthyroid 
      orbitopathy; (2) active dysthyroid orbitopathy; (3) chronic or recurrent 
      dysthyroid orbitopathy; or (4) dysthyroid orbitopathy characterized by limited 
      myopathy. The serum IgE levels of all these groups were compared with 26 healthy, 
      nonatopic volunteers. The mean IgE levels of groups 3 and 4 were significantly 
      higher than the mean IgE level of the control group as well as that of the group 
      with stable dysthyroid orbitopathy. Furthermore, serial readings on several 
      patients were consistent with the hypothesis that serum IgE is elevated in 
      connection with certain stages of rapid dysthyroid orbitopathy progression and 
      also with two unusual clinical forms of dysthyroid orbitopathy.
FAU - Raikow, R B
AU  - Raikow RB
AD  - Department of Ophthalmology, Allegheny General Hospital, Pittsburgh, PA.
FAU - Tyutyunikov, A
AU  - Tyutyunikov A
FAU - Kennerdell, J S
AU  - Kennerdell JS
FAU - Kazim, M
AU  - Kazim M
FAU - Dalbow, M H
AU  - Dalbow MH
FAU - Scalise, D
AU  - Scalise D
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Ophthalmology
JT  - Ophthalmology
JID - 7802443
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Graves Disease/*blood/pathology
MH  - Humans
MH  - Immunoglobulin E/*blood
EDAT- 1992/03/01 00:00
MHDA- 1992/03/01 00:01
CRDT- 1992/03/01 00:00
PHST- 1992/03/01 00:00 [pubmed]
PHST- 1992/03/01 00:01 [medline]
PHST- 1992/03/01 00:00 [entrez]
AID - S0161-6420(92)31964-5 [pii]
AID - 10.1016/s0161-6420(92)31964-5 [doi]
PST - ppublish
SO  - Ophthalmology. 1992 Mar;99(3):361-5. doi: 10.1016/s0161-6420(92)31964-5.