PMID- 15656103
OWN - NLM
STAT- MEDLINE
DCOM- 20050222
LR  - 20191109
IS  - 0939-3889 (Print)
IS  - 0939-3889 (Linking)
VI  - 14
IP  - 4
DP  - 2004
TI  - Optimisation in stereotactic radiosurgery of AVMs: I. Mathematical 
      considerations.
PG  - 213-21
AB  - One forward-planning method and five inverse-planning methods for optimisation of 
      treatment in radiation therapy were compared in the particular case of 
      radiosurgery with micro-multi-leaves collimator (MMLC) and arc therapy. The 
      "manual" method, two matrix methods (singular value decomposition and 
      non-negative least square fit), two gradient methods (quasi-Newton and conjugate 
      gradient algorithms) and the "simulated annealing" stochastic method were 
      investigated. The performance of these methods was assessed in terms of the speed 
      of convergence to an optimum, the ability to account for the organs at risk, and 
      probability of targeted success. The study employed an adapted version of the 
      GRATIS treatment planning system. A group of 22 patients previously treated by 
      arc therapy for arteriovenous malformations (AVMs) were studied to evaluate the 
      performance of the various optimisation methods for MMLC and arc therapy. The 
      conjugate gradient method proved to be the most appropriate for most cases.
FAU - Tercier, Pierre-Alain
AU  - Tercier PA
AD  - Institut Universitaire de Radiophysique Appliquee, Lausanne. 
      Pierre_Alain.Tercier@freesurf.ch
FAU - Aroua, Abbas
AU  - Aroua A
FAU - Valley, Jean-Francois
AU  - Valley JF
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Z Med Phys
JT  - Zeitschrift fur medizinische Physik
JID - 100886455
SB  - IM
MH  - Algorithms
MH  - Computer Simulation
MH  - Humans
MH  - Mathematics
MH  - Models, Theoretical
MH  - Radiosurgery/*methods
MH  - Stereotaxic Techniques
EDAT- 2005/01/20 09:00
MHDA- 2005/02/23 09:00
CRDT- 2005/01/20 09:00
PHST- 2005/01/20 09:00 [pubmed]
PHST- 2005/02/23 09:00 [medline]
PHST- 2005/01/20 09:00 [entrez]
AID - 10.1078/0939-3889-00227 [doi]
PST - ppublish
SO  - Z Med Phys. 2004;14(4):213-21. doi: 10.1078/0939-3889-00227.