PMID- 15658468
OWN - NLM
STAT- MEDLINE
DCOM- 20050304
LR  - 20061115
IS  - 0047-1860 (Print)
IS  - 0047-1860 (Linking)
VI  - 52
IP  - 11
DP  - 2004 Nov
TI  - [Relationship between aneuploidy of chromosome 17 and amplification of HER-2/neu 
      gene in the different histological type of breast cancer].
PG  - 897-9
AB  - We examined the relationship between the aneuploidy of chromosome 17 and the 
      amplification of HER-2/neu gene by fluorescence in situ hybridization (FISH) in 
      the different histological type of breast cancer (n = 55). 51 patients recognized 
      the aneuploidy that consisted of 37 patients of monosomy and 14 patients of 
      polysomy. In the scirrhous carcinoma, HER-2/neu gene was amplified in 15% of 
      monosomy cases, but it was not amplified in all polysomy cases. In the 
      papillotubular carcinoma, HER-2/neu gene was contrastively amplified in all 
      polysomy cases, but it was not amplified in all monosomy cases. No case of 
      solid-tubular carcinoma recognized the amplification. The relation was different 
      according to the histological type of breast cancer.
FAU - Kuroso, Kazuko
AU  - Kuroso K
AD  - Department of Pathology, Dokkyo University School of Medicine, Koshigaya 
      Hospital, Koshigaya 343-8555.
FAU - Ueda, Yoshihiko
AU  - Ueda Y
FAU - Mori, Yoshiomi
AU  - Mori Y
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Byori
JT  - Rinsho byori. The Japanese journal of clinical pathology
JID - 2984781R
SB  - IM
MH  - Adenocarcinoma/genetics
MH  - Adenocarcinoma, Scirrhous/genetics
MH  - *Aneuploidy
MH  - Breast Neoplasms/*genetics
MH  - Carcinoma, Papillary/genetics
MH  - Chromosomes, Human, Pair 17/*genetics
MH  - *Gene Amplification
MH  - Genes, erbB-2/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
EDAT- 2005/01/22 09:00
MHDA- 2005/03/05 09:00
CRDT- 2005/01/22 09:00
PHST- 2005/01/22 09:00 [pubmed]
PHST- 2005/03/05 09:00 [medline]
PHST- 2005/01/22 09:00 [entrez]
PST - ppublish
SO  - Rinsho Byori. 2004 Nov;52(11):897-9.