PMID- 15663537
OWN - NLM
STAT- MEDLINE
DCOM- 20050218
LR  - 20220414
IS  - 1744-9979 (Print)
IS  - 1744-9979 (Linking)
VI  - 8
IP  - 5
DP  - 2004 Oct
TI  - Plasmapheresis treatment in Guillain-Barre syndrome: potential benefit over IVIg 
      in patients with axonal involvement.
PG  - 409-12
AB  - Response to therapeutic plasma exchange (TPE) was evaluated in patients diagnosed 
      with Guillain-Barre Syndrome (GBS). Our aim was to assess response to TPE in 
      patients who had failed treatment with intravenous immune globulin (IVIg). We 
      conducted a retrospective chart review of 10 patients with the diagnosis of 
      Guillain-Barre Syndrome who required TPE. Patients were identified by reviewing 
      data from log books for TPE at The University of Connecticut Health Center, 
      Farmington CT, USA. Patients who had failed IVIg treatment prior to being 
      referred for TPE were also identified. Eight out of 10 patients treated with TPE 
      showed improvement in their neurological exam. Four patients had axonal 
      involvement on electromyelogram (EMG). Three patients were referred for TPE after 
      failing IVIg treatment. All three of these had axonal involvement on EMG. Three 
      of the four patients with axonal involvement demonstrated improvement with TPE. 
      TPE may be a superior treatment option as compared to IVIg in patients with GBS 
      and EMG findings of axonal involvement.
FAU - Dada, Mohammed Atiq
AU  - Dada MA
AD  - Division of Nephrology, University of Connecticut Health Center, Farmington, CT 
      06032-1405, USA.
FAU - Kaplan, Andre A
AU  - Kaplan AA
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Ther Apher Dial
JT  - Therapeutic apheresis and dialysis : official peer-reviewed journal of the 
      International Society for Apheresis, the Japanese Society for Apheresis, the 
      Japanese Society for Dialysis Therapy
JID - 101181252
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Axons/physiology
MH  - Guillain-Barre Syndrome/physiopathology/*therapy
MH  - Humans
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - *Plasma Exchange
MH  - *Plasmapheresis
MH  - Retreatment
MH  - Retrospective Studies
MH  - Treatment Failure
EDAT- 2005/01/25 09:00
MHDA- 2005/02/19 09:00
CRDT- 2005/01/25 09:00
PHST- 2005/01/25 09:00 [pubmed]
PHST- 2005/02/19 09:00 [medline]
PHST- 2005/01/25 09:00 [entrez]
AID - TAP183 [pii]
AID - 10.1111/j.1526-0968.2004.00183.x [doi]
PST - ppublish
SO  - Ther Apher Dial. 2004 Oct;8(5):409-12. doi: 10.1111/j.1526-0968.2004.00183.x.