PMID- 15674962
OWN - NLM
STAT- MEDLINE
DCOM- 20050527
LR  - 20181201
IS  - 1469-493X (Electronic)
IS  - 1361-6137 (Linking)
IP  - 1
DP  - 2005 Jan 25
TI  - Hyperbaric oxygen therapy for promoting fracture healing and treating fracture 
      non-union.
PG  - CD004712
AB  - BACKGROUND: Hyperbaric oxygen therapy (HBOT) consists of intermittently 
      administering 100% oxygen at pressures greater than one atmosphere absolute (ATA) 
      in a pressure vessel. This technology has been used to treat a variety of 
      diseases and has been described as helping patients who have delayed healing or 
      established non-union of bony fractures. OBJECTIVES: The aim of this review was 
      to assess the evidence for the benefit of hyperbaric oxygen treatment (HBOT) for 
      the treatment of delayed bony healing and established non-union of bony 
      fractures. SEARCH STRATEGY: We searched the Cochrane Musculoskeletal Injuries 
      Group trials register (to January week 3, 2004), the Cochrane Central Register of 
      Controlled Trials (The Cochrane Library Issue 4, 2003), MEDLINE (OVID 1966 to 
      January week 3, 2004), CINAHL (OVID 1982 to January week 3, 2004), EMBASE (OVID 
      1980 to February 2004), the locally developed Database of Randomised Controlled 
      Trials in Hyperbaric Medicine (available at www.hboevidence.com) from inception 
      to March 2004, and reference lists of articles. SELECTION CRITERIA: We aimed to 
      include all randomised controlled trials that compared the effect of HBOT with no 
      HBOT (no treatment or sham). DATA COLLECTION AND ANALYSIS: Two authors using 
      standardised forms attempted to extract data independently. MAIN RESULTS: No 
      trials met the inclusion criteria. We excluded one trial that compared HBOT with 
      no treatment because no clinical outcomes were reported. AUTHORS' CONCLUSIONS: 
      This systematic review failed to locate any relevant clinical evidence to support 
      or refute the effectiveness of HBOT for the management of delayed union or 
      established non-union of bony fractures. Good quality clinical trials are needed 
      to define the role, if any, of HBOT in the treatment of these injuries.
FAU - Bennett, M H
AU  - Bennett MH
AD  - Diving and Hyperbaric Medicine, Prince of Wales Hospital, Barker Street, 
      Randwick, NSW, Australia, 2031. m.bennett@unsw.edu.au
FAU - Stanford, R
AU  - Stanford R
FAU - Turner, R
AU  - Turner R
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20050125
PL  - England
TA  - Cochrane Database Syst Rev
JT  - The Cochrane database of systematic reviews
JID - 100909747
SB  - IM
UIN - Cochrane Database Syst Rev. 2012;3:CD004712. PMID: 22419299
MH  - *Fracture Healing
MH  - Fractures, Ununited/physiopathology/*therapy
MH  - Humans
MH  - *Hyperbaric Oxygenation
RF  - 31
EDAT- 2005/01/28 09:00
MHDA- 2005/05/28 09:00
CRDT- 2005/01/28 09:00
PHST- 2005/01/28 09:00 [pubmed]
PHST- 2005/05/28 09:00 [medline]
PHST- 2005/01/28 09:00 [entrez]
AID - 10.1002/14651858.CD004712.pub2 [doi]
PST - epublish
SO  - Cochrane Database Syst Rev. 2005 Jan 25;(1):CD004712. doi: 
      10.1002/14651858.CD004712.pub2.