PMID- 15675518
OWN - NLM
STAT- MEDLINE
DCOM- 20050310
LR  - 20190827
IS  - 0910-6340 (Print)
IS  - 0910-6340 (Linking)
VI  - 21
IP  - 1
DP  - 2005 Jan
TI  - Rapid enantioseparation of 1-aminoindan by microchip electrophoresis with 
      linear-imaging UV detection.
PG  - 61-5
AB  - Chiral separations of 1-aminoindan (AI) by cyclodextrin electrokinetic 
      chromatography (CDEKC) were investigated on microfluidic quartz chips. By using a 
      microchip electrophoresis (MCE) instrument equipped with a linear-imaging UV 
      detector, the separation process of the enantiomeric compounds was observed. When 
      sulfated beta-cyclodextrin was employed as a chiral selector, the baseline 
      separation of AI could be achieved within 1 min with a high repeatability. The 
      relative standard deviation of the migration time was less than 6%. The fastest 
      separation was achieved in 14 s, utilizing a separation length of only 6.1 mm. 
      These results show that the MCE analysis employing a linear imaging UV detector 
      has a significant potential for fast chiral analysis.
FAU - Kitagawa, Fumihiko
AU  - Kitagawa F
AD  - Department of Material Chemistry, Graduate School of Engineering, Kyoto 
      University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan. 
      fkitagawa@mbox.kudpc.kyoto-u.ac.jp
FAU - Aizawa, Shiori
AU  - Aizawa S
FAU - Otsuka, Koji
AU  - Otsuka K
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Anal Sci
JT  - Analytical sciences : the international journal of the Japan Society for 
      Analytical Chemistry
JID - 8511078
RN  - 0 (Indans)
RN  - 34698-41-4 (1-aminoindan)
SB  - IM
MH  - Electrophoresis, Microchip
MH  - Indans/chemistry/*isolation & purification
EDAT- 2005/01/29 09:00
MHDA- 2005/03/11 09:00
CRDT- 2005/01/29 09:00
PHST- 2005/01/29 09:00 [pubmed]
PHST- 2005/03/11 09:00 [medline]
PHST- 2005/01/29 09:00 [entrez]
AID - 10.2116/analsci.21.61 [doi]
PST - ppublish
SO  - Anal Sci. 2005 Jan;21(1):61-5. doi: 10.2116/analsci.21.61.